hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10275.1
Complex Portal: CPX-23700
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CTAG1A | Cancer/testis antigen 1 (Autoimmunogenic cancer/testis antigen NY-ESO-1) (Cancer/testis antigen 6.1) (CT6.1) (L antigen family member 2) (LAGE-2) | 5 | UniProt NCBI |
| CEP250 | Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2) | 5 | UniProt NCBI |
| NUP62CL | Nucleoporin-62 C-terminal-like protein | 3 | UniProt NCBI |
| NUP58 | Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1) | 5 | UniProt NCBI |
| NUP54 | Nucleoporin p54 (54 kDa nucleoporin) | 5 | UniProt NCBI |
| TET3 | Methylcytosine dioxygenase TET3 (EC 1.14.11.80) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3998 | 0.0197951791935 | 0.4 | NUP58 NUP54 | Prader Willi and Angelman syndrome |
| KEGG:03013 | 0.0226459969921 | 0.4 | NUP58 NUP54 | Nucleocytoplasmic transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NUP54 | NUP58 | 0.999 | 0.938 |
mutually_exclusive (Q9H1M0)
structurally_consistent (dimer) |
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| NUP54 | NUP62CL | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NUP58 | NUP62CL | 0.999 |
mutually_exclusive (Q7Z3B4)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NUP62CL | TET3 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NUP62CL | CTAG1A | 0.978 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CEP250 | NUP54 | 0.958 | 0.307333333333 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TET3 | CTAG1A | 0.415 | bioplex3_WMM WMM_only | ||
| CEP250 | NUP58 | 0.201 | 0.098 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| CEP250 | NUP62CL | 0.187 | bioplex_WMM bioplex3_WMM WMM_only | ||
| NUP54 | TET3 | 0.093 | bioplex3_WMM WMM_only | ||
| NUP54 | CTAG1A | 0.093 | 0.034 | bioplex3_WMM WMM_only | |
| NUP58 | CTAG1A | 0.027 | 0.076 | bioplex3_WMM WMM_only | |
| NUP58 | TET3 | 0.016 | bioplex3_WMM gupta_WMM WMM_only |
Related Complexes