hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10280.1
Complex Portal: CPX-15388
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KLK7 | Kallikrein-7 (hK7) (EC 3.4.21.117) (Serine protease 6) (Stratum corneum chymotryptic enzyme) (hSCCE) | 5 | UniProt NCBI |
| VAV1 | Proto-oncogene vav | 5 | UniProt NCBI |
| PLBD1 | Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C] | 5 | UniProt NCBI |
| ST8SIA1 | Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.3.8) (Alpha-2,8-sialyltransferase 8A) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Sialyltransferase 8A) (SIAT8-A) (Sialyltransferase St8Sia I) (ST8SiaI) | 5 | UniProt NCBI |
| KPRP | Keratinocyte proline-rich protein (hKPRP) | 5 | UniProt NCBI |
| MYCBPAP | MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1) | 5 | UniProt NCBI |
| CABS1 | Calcium-binding and spermatid-specific protein 1 (Testis development protein NYD-SP26) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0461402 | 0.0196737861195 | 0.333333333333 | KLK7 KPRP | skin 1; cells in corneal layer[>=Medium] |
| HPA:0461401 | 0.0432385231981 | 0.333333333333 | KLK7 KPRP | skin 1; cells in corneal layer[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CABS1 | PLBD1 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| VAV1 | KLK7 | 0.982 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ST8SIA1 | KLK7 | 0.978 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KLK7 | PLBD1 | 0.971 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KPRP | PLBD1 | 0.971 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| ST8SIA1 | KPRP | 0.966 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KPRP | KLK7 | 0.959 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | ||
| MYCBPAP | KLK7 | 0.959 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| VAV1 | PLBD1 | 0.953 | 0.1 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| KPRP | CABS1 | 0.923 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KPRP | MYCBPAP | 0.915 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KPRP | VAV1 | 0.425 | 0.1 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM |
Related Complexes