hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10281.1
Complex Portal: CPX-21575
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AARS1 | Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42) | 5 | UniProt NCBI |
| PLS3 | Plastin-3 (T-plastin) | 5 | UniProt NCBI |
| EZR | Ezrin (Cytovillin) (Villin-2) (p81) | 5 | UniProt NCBI |
| RDX | Radixin | 5 | UniProt NCBI |
| PLS1 | Plastin-1 (Intestine-specific plastin) (I-plastin) | 5 | UniProt NCBI |
| MSN | Moesin (Membrane-organizing extension spike protein) | 5 | UniProt NCBI |
| TES | Testin (TESS) | 5 | UniProt NCBI |
| EFHD2 | EF-hand domain-containing protein D2 (Swiprosin-1) | 4 | UniProt NCBI |
| SNN | Stannin (AG8_1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9662361 | 0.0161658624528 | 0.333333333333 | RDX PLS1 | Sensory processing of sound by outer hair cells of the cochlea |
| REAC:R-HSA-9662360 | 0.0326270815028 | 0.333333333333 | RDX PLS1 | Sensory processing of sound by inner hair cells of the cochlea |
| REAC:R-HSA-9659379 | 0.0379731829042 | 0.333333333333 | RDX PLS1 | Sensory processing of sound |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PLS1 | PLS3 | 1.0 | 0.198 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| MSN | RDX | 1.0 | 0.512 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () treiber_WMM | |
| EZR | RDX | 0.999 | 0.35 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM treiber_WMM | |
| MSN | EZR | 0.999 | 0.566 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 gupta_WMM treiber_WMM | |
| PLS1 | MSN | 0.995 | 0.262 | hein_WMM bioplex_WMM Guru bioplex3_WMM fraction treiber_WMM | |
| PLS1 | EFHD2 | 0.993 | 0.088 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| TES | EFHD2 | 0.992 | 0.154 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| PLS3 | EFHD2 | 0.989 | 0.146 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| PLS3 | TES | 0.985 | 0.198 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| TES | MSN | 0.981 | 0.202 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| AARS1 | EFHD2 | 0.981 | 0.0840983606557 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| MSN | EFHD2 | 0.963 | 0.368 | hein_WMM bioplex_WMM Guru bioplex3_WMM gupta_WMM fraction | |
| SNN | TES | 0.954 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TES | AARS1 | 0.945 | 0.162098360656 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| PLS3 | EZR | 0.751 | 0.314 | bioplex_WMM Guru bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | |
| PLS1 | TES | 0.71 | 0.084 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| PLS1 | EZR | 0.704 | 0.168 | bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| PLS3 | AARS1 | 0.664 | 0.264 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM | |
| PLS1 | AARS1 | 0.593 | 0.0800983606557 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| PLS3 | RDX | 0.581 | 0.286 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM | |
| MSN | AARS1 | 0.548 | 0.448 | hein_WMM bioplex_WMM bioplex3_WMM fraction treiber_WMM | |
| PLS1 | RDX | 0.538 | 0.214 | bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction | |
| PLS3 | MSN | 0.433 | 0.418 | bioplex_WMM Guru bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | |
| TES | EZR | 0.248 | 0.202 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| EZR | EFHD2 | 0.127 | 0.088 | bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction | |
| AARS1 | RDX | 0.088 | 0.238 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| TES | RDX | 0.054 | 0.258 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| SNN | PLS3 | 0.022 | bioplex3_HEK293 bioplex () | ||
| EZR | AARS1 | 0.016 | 0.304 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM | |
| EFHD2 | RDX | 0.011 | 0.148 | bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction | |
| SNN | MSN | 0.006 | bioplex3_HEK293 bioplex () | ||
| SNN | EZR | 0.005 | bioplex3_HEK293 bioplex () |
Related Complexes