hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10302.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
AARS1	Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42)	5	UniProt NCBI
TCEA1	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o)	5	UniProt NCBI
YARS1	Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]	5	UniProt NCBI
PIN1	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase Pin1) (PPIase Pin1) (Rotamase Pin1)	5	UniProt NCBI
RBM12	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN)	4	UniProt NCBI
FEN1	Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1)	5	UniProt NCBI
NARS1	Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) (Asparaginyl-tRNA synthetase 1)	5	UniProt NCBI
VRK1	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)	5	UniProt NCBI
IDH2	Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-379716	7.6950453904e-05	0.333333333333	AARS1 NARS1 YARS1	Cytosolic tRNA aminoacylation
KEGG:00970	9.95160164508e-05	0.333333333333	AARS1 NARS1 YARS1	Aminoacyl-tRNA biosynthesis
REAC:R-HSA-379724	0.000434042545956	0.333333333333	AARS1 NARS1 YARS1	tRNA Aminoacylation
HPA:0040082	0.000639027362146	1.0	RBM12 PIN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1 FEN1	bone marrow; hematopoietic cells[>=Medium]
HPA:0310431	0.00353584723232	1.0	RBM12 PIN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1 FEN1	lymph node; germinal center cells[>=Low]
HPA:0310442	0.0111871456353	0.888888888889	RBM12 FEN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1	lymph node; non-germinal center cells[>=Medium]
HPA:0600432	0.0147242547642	0.888888888889	RBM12 FEN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1	tonsil; germinal center cells[>=Medium]
HPA:0040000	0.0281468034324	1.0	RBM12 PIN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1 FEN1	bone marrow
HPA:0040081	0.0281468034324	1.0	RBM12 PIN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1 FEN1	bone marrow; hematopoietic cells[>=Low]
HPA:0310000	0.0303405882675	1.0	RBM12 PIN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1 FEN1	lymph node
HPA:0160051	0.0458948293771	1.0	RBM12 PIN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1 FEN1	endometrium 1; glandular cells[>=Low]
HPA:0310432	0.0460528081793	0.777777777778	RBM12 FEN1 AARS1 IDH2 TCEA1 VRK1 YARS1	lymph node; germinal center cells[>=Medium]
HPA:0080000	0.0490590626292	1.0	RBM12 PIN1 AARS1 IDH2 TCEA1 VRK1 YARS1 NARS1 FEN1	caudate
CORUM:6948	0.0499842271994	0.111111111111	IDH2	Isocitrate dehydrogenase [NADP], mitochondrial

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
TCEA1	VRK1	0.992	0.108	bioplex_WMM bioplex3_WMM fraction
VRK1	RBM12	0.988	0.034	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
FEN1	VRK1	0.984	0.106	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction
RBM12	NARS1	0.978	0.086	bioplex_WMM bioplex3_WMM WMM_only
VRK1	NARS1	0.977	0.068	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
VRK1	IDH2	0.97	0.056	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
AARS1	YARS1	0.968	0.778	bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM WMM_only
PIN1	NARS1	0.966	0.122	bioplex_WMM bioplex3_WMM gupta_WMM WMM_only
FEN1	NARS1	0.962	0.184	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM
PIN1	RBM12	0.961	0.172	bioplex_WMM bioplex3_WMM gupta_WMM fraction
VRK1	YARS1	0.958	0.202	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
AARS1	NARS1	0.956	0.302	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM
AARS1	IDH2	0.953	0.262	bioplex_WMM bioplex3_WMM boldt gupta_WMM fraction boldt_WMM
RBM12	YARS1	0.926	0.076	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
FEN1	YARS1	0.92	0.206	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM
FEN1	TCEA1	0.918	0.172	bioplex_WMM bioplex3_WMM fraction treiber_WMM
RBM12	IDH2	0.909	0.11	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
TCEA1	YARS1	0.894	0.298	bioplex_WMM bioplex3_WMM WMM_only treiber_WMM
TCEA1	RBM12	0.892	0.124	bioplex_WMM bioplex3_WMM WMM_only
PIN1	VRK1	0.882	0.036	bioplex_WMM bioplex3_WMM WMM_only
FEN1	RBM12	0.872	0.158	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
AARS1	RBM12	0.871	0.0760983606557	bioplex_WMM bioplex3_WMM WMM_only
FEN1	IDH2	0.869	0.248	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM treiber_WMM
YARS1	NARS1	0.866	0.496	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM
TCEA1	NARS1	0.821	0.232	bioplex_WMM bioplex3_WMM fraction
YARS1	IDH2	0.791	0.224	bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM WMM_only
FEN1	PIN1	0.786	0.204	bioplex_WMM bioplex3_WMM gupta_WMM WMM_only
FEN1	AARS1	0.709	0.27	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM
NARS1	IDH2	0.676	0.108	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM
AARS1	VRK1	0.659	0.182	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
PIN1	AARS1	0.579	0.168098360656	bioplex_WMM bioplex3_WMM gupta_WMM fraction
TCEA1	PIN1	0.541	0.116	bioplex_WMM bioplex3_WMM fraction
PIN1	YARS1	0.431	0.242	bioplex_WMM bioplex3_WMM gupta_WMM WMM_only
TCEA1	AARS1	0.284	0.152	bioplex_WMM bioplex3_WMM fraction
PIN1	IDH2	0.263	0.126	bioplex_WMM bioplex3_WMM fraction
TCEA1	IDH2	0.043	0.146	bioplex_WMM bioplex3_WMM WMM_only treiber_WMM

Related Complexes

Genename	Complexes
AARS1	huMAP3_03533.1 huMAP3_04783.1 huMAP3_07456.1 huMAP3_08138.1 huMAP3_09323.1 huMAP3_10115.1 huMAP3_10281.1 huMAP3_10302.1 huMAP3_11534.1 huMAP3_14442.1
TCEA1	huMAP3_02022.1 huMAP3_03576.1 huMAP3_04535.1 huMAP3_06325.1 huMAP3_07450.1 huMAP3_09323.1 huMAP3_10043.1 huMAP3_10088.1 huMAP3_10302.1 huMAP3_13998.1 huMAP3_14625.1 huMAP3_14982.1
YARS1	huMAP3_04783.1 huMAP3_10115.1 huMAP3_10302.1 huMAP3_13998.1 huMAP3_14442.1
PIN1	huMAP3_02670.1 huMAP3_06437.1 huMAP3_07518.1 huMAP3_08588.1 huMAP3_09159.1 huMAP3_10088.1 huMAP3_10115.1 huMAP3_10290.1 huMAP3_10302.1 huMAP3_11627.1 huMAP3_14442.1
RBM12	huMAP3_04758.1 huMAP3_06526.1 huMAP3_07310.1 huMAP3_08588.1 huMAP3_09159.1 huMAP3_10088.1 huMAP3_10115.1 huMAP3_10302.1 huMAP3_14982.1
FEN1	huMAP3_00990.1 huMAP3_01087.1 huMAP3_03894.1 huMAP3_06325.1 huMAP3_08171.1 huMAP3_10115.1 huMAP3_10302.1 huMAP3_13998.1 huMAP3_14982.1
NARS1	huMAP3_06325.1 huMAP3_07310.1 huMAP3_10088.1 huMAP3_10115.1 huMAP3_10302.1 huMAP3_14982.1
VRK1	huMAP3_03576.1 huMAP3_06325.1 huMAP3_07310.1 huMAP3_09323.1 huMAP3_10088.1 huMAP3_10115.1 huMAP3_10302.1 huMAP3_13998.1 huMAP3_14982.1
IDH2	huMAP3_08138.1 huMAP3_09323.1 huMAP3_10115.1 huMAP3_10302.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10302.1