hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10310.1
Complex Portal: CPX-12815
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TSC22D4 | TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) | 5 | UniProt NCBI |
| CA10 | Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CA-RP X) (CARP X) (Cerebral protein 15) | 3 | UniProt NCBI |
| NRBP1 | Nuclear receptor-binding protein | 5 | UniProt NCBI |
| NRBP2 | Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16) | 4 | UniProt NCBI |
| SH2B3 | SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) | 5 | UniProt NCBI |
| TSC22D1 | TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein) | 5 | UniProt NCBI |
| MYO7A | Unconventional myosin-VIIa | 5 | UniProt NCBI |
| TSC22D2 | TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4) | 4 | UniProt NCBI |
| TSC22D3 | TSC22 domain family protein 3 (DSIP-immunoreactive peptide) (Protein DIP) (hDIP) (Delta sleep-inducing peptide immunoreactor) (Glucocorticoid-induced leucine zipper protein) (GILZ) (TSC-22-like protein) (TSC-22-related protein) (TSC-22R) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6530 | 0.0499842271994 | 0.111111111111 | MYO7A | MYO7A-PDZD7 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TSC22D4 | NRBP1 | 1.0 | 0.2 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| TSC22D4 | TSC22D2 | 1.0 | 0.06 |
mutually_exclusive (Q99576)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TSC22D3 | NRBP1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | ||
| TSC22D4 | TSC22D1 | 1.0 | 0.072 |
mutually_exclusive (Q99576)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TSC22D2 | NRBP1 | 1.0 | 0.21 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TSC22D2 | TSC22D3 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TSC22D1 | TSC22D3 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TSC22D4 | TSC22D3 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TSC22D4 | NRBP2 | 0.999 | 0.034 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TSC22D1 | NRBP1 | 0.999 | 0.132 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NRBP2 | NRBP1 | 0.996 | 0.096 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TSC22D4 | SH2B3 | 0.993 | 0.11 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TSC22D4 | CA10 | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NRBP2 | TSC22D3 | 0.982 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NRBP2 | CA10 | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NRBP2 | TSC22D1 | 0.962 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| TSC22D1 | TSC22D2 | 0.962 | 0.228 |
mutually_exclusive (Q99576)
|
bioplex_WMM bioplex3_WMM WMM_only |
| NRBP1 | CA10 | 0.959 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| MYO7A | NRBP1 | 0.957 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only | |
| NRBP2 | TSC22D2 | 0.951 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only | |
| TSC22D1 | CA10 | 0.913 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| SH2B3 | TSC22D2 | 0.904 | 0.062 | bioplex3_WMM WMM_only | |
| SH2B3 | NRBP1 | 0.848 | 0.074 | bioplex3_WMM WMM_only | |
| TSC22D4 | MYO7A | 0.779 | 0.058 | bioplex3_WMM WMM_only | |
| SH2B3 | TSC22D3 | 0.715 | bioplex3_WMM WMM_only | ||
| NRBP2 | MYO7A | 0.698 | 0.072 | bioplex3_WMM WMM_only | |
| NRBP2 | SH2B3 | 0.698 | 0.07 | bioplex3_WMM WMM_only | |
| SH2B3 | TSC22D1 | 0.676 | 0.12 | bioplex3_WMM WMM_only | |
| TSC22D1 | MYO7A | 0.016 | 0.062 | bioplex3_WMM WMM_only |
Related Complexes