hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10319.1
Complex Portal: CPX-14878
Confidence: Medium High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TMEM182 | Transmembrane protein 182 | 5 | UniProt   NCBI |
| CKLF | Chemokine-like factor (C32) | 5 | UniProt   NCBI |
| GLIPR1 | Glioma pathogenesis-related protein 1 (GliPR 1) (Protein RTVP-1) | 4 | UniProt   NCBI |
| RIT1 | GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) | 5 | UniProt   NCBI |
| RIT2 | GTP-binding protein Rit2 (EC 3.6.5.2) (Ras-like protein expressed in neurons) (Ras-like without CAAX protein 2) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   REAC:R-HSA-187706 | 4.55977246808e-05 | 0.4 | RIT2 RIT1 | Signalling to p38 via RIT and RIN |
|   REAC:R-HSA-187687 | 0.00492422076745 | 0.4 | RIT2 RIT1 | Signalling to ERKs |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  GLIPR1 |  RIT1 | 0.997 | 0.11           |          | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
|  RIT1 |  RIT2 | 0.989 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  CKLF |  GLIPR1 | 0.98 | 0.154           |          | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
|  RIT1 |  TMEM182 | 0.958 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
|  CKLF |  RIT1 | 0.902 | 0.104           |          | bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| TMEM182 | huMAP3_05241.1 huMAP3_10319.1 huMAP3_12467.1 |
| CKLF | huMAP3_04398.1 huMAP3_10319.1 huMAP3_11695.1 huMAP3_13790.1 |
| GLIPR1 | huMAP3_04398.1 huMAP3_10319.1 huMAP3_11695.1 huMAP3_13790.1 |
| RIT1 | huMAP3_05241.1 huMAP3_10319.1 huMAP3_11695.1 huMAP3_13790.1 |
| RIT2 | huMAP3_05241.1 huMAP3_10319.1 huMAP3_11695.1 huMAP3_13790.1 |