hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10334.1
Complex Portal: CPX-13418
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CRYZ | Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) | 5 | UniProt NCBI |
| PCK2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) (Phosphoenolpyruvate carboxykinase 2, mitochondrial) (mtPCK2) | 5 | UniProt NCBI |
| IARS2 | Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS) | 5 | UniProt NCBI |
| NIPSNAP1 | Protein NipSnap homolog 1 (NipSnap1) | 2 | UniProt NCBI |
| HSD17B8 | (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (HSD17B8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Protein Ke6) (Ke6) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) | 5 | UniProt NCBI |
| CYP24A1 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase) (Vitamin D(3) 24-hydroxylase) (EC 1.14.15.16) (Cytochrome P450 24A1) (Cytochrome P450-CC24) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IARS2 | PCK2 | 0.986 | 0.168 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction treiber_WMM | |
| IARS2 | CRYZ | 0.971 | 0.138 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| HSD17B8 | IARS2 | 0.966 | 0.096 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction | |
| HSD17B8 | CYP24A1 | 0.958 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IARS2 | NIPSNAP1 | 0.957 | 0.194 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM | |
| CYP24A1 | IARS2 | 0.66 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CRYZ | PCK2 | 0.539 | 0.106 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction | |
| CYP24A1 | NIPSNAP1 | 0.252 | bioplex3_WMM WMM_only | ||
| CYP24A1 | CRYZ | 0.236 | bioplex3_WMM WMM_only | ||
| HSD17B8 | NIPSNAP1 | 0.175 | 0.1 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| CYP24A1 | PCK2 | 0.082 | bioplex3_WMM WMM_only | ||
| NIPSNAP1 | CRYZ | 0.066 | 0.194 | bioplex_WMM bioplex3_WMM WMM_only | |
| NIPSNAP1 | PCK2 | 0.02 | 0.146 | bioplex_WMM bioplex3_WMM WMM_only | |
| HSD17B8 | PCK2 | 0.008 | 0.132 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HSD17B8 | CRYZ | 0.005 | 0.08 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes