hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10335.1
Complex Portal: CPX-20136
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADAM19 | Disintegrin and metalloproteinase domain-containing protein 19 (ADAM 19) (EC 3.4.24.-) (Meltrin-beta) (Metalloprotease and disintegrin dendritic antigen marker) (MADDAM) | 5 | UniProt NCBI |
| ADAMTS14 | A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-) | 5 | UniProt NCBI |
| LAMC3 | Laminin subunit gamma-3 (Laminin-12 subunit gamma) (Laminin-14 subunit gamma) (Laminin-15 subunit gamma) | 5 | UniProt NCBI |
| LTBP3 | Latent-transforming growth factor beta-binding protein 3 (LTBP-3) | 5 | UniProt NCBI |
| TGFB1 | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)] | 5 | UniProt NCBI |
| DTWD1 | tRNA-uridine aminocarboxypropyltransferase 1 (EC 2.5.1.25) (DTW domain-containing protein 1) | 4 | UniProt NCBI |
| CFC1 | Cryptic protein (Cryptic family protein 1) | 5 | UniProt NCBI |
| LY86 | Lymphocyte antigen 86 (Ly-86) (Protein MD-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1474244 | 0.000377209111577 | 0.571428571429 | ADAMTS14 LTBP3 ADAM19 LAMC3 | Extracellular matrix organization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DTWD1 | LY86 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| LY86 | ADAMTS14 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| LY86 | LAMC3 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| LY86 | ADAM19 | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TGFB1 | LAMC3 | 0.99 | 0.392 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ADAMTS14 | CFC1 | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TGFB1 | LTBP3 | 0.983 | 0.426 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CFC1 | ADAM19 | 0.98 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TGFB1 | LY86 | 0.977 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| LTBP3 | LY86 | 0.975 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CFC1 | LAMC3 | 0.96 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TGFB1 | CFC1 | 0.793 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ADAMTS14 | ADAM19 | 0.634 | bioplex3_WMM WMM_only | ||
| ADAM19 | LAMC3 | 0.438 | bioplex3_WMM WMM_only | ||
| ADAMTS14 | LAMC3 | 0.384 | bioplex3_WMM WMM_only | ||
| DTWD1 | ADAMTS14 | 0.269 | bioplex3_WMM WMM_only | ||
| TGFB1 | ADAMTS14 | 0.263 | bioplex3_WMM WMM_only | ||
| LTBP3 | ADAM19 | 0.253 | bioplex3_WMM WMM_only | ||
| LTBP3 | LAMC3 | 0.23 | 0.136 | bioplex3_WMM WMM_only | |
| LTBP3 | ADAMTS14 | 0.214 | bioplex3_WMM WMM_only | ||
| DTWD1 | LAMC3 | 0.188 | 0.102 | bioplex3_WMM WMM_only | |
| DTWD1 | ADAM19 | 0.126 | bioplex3_WMM WMM_only | ||
| DTWD1 | TGFB1 | 0.076 | 0.238830827397 | bioplex3_WMM WMM_only | |
| DTWD1 | LTBP3 | 0.074 | 0.05 | bioplex3_WMM WMM_only | |
| TGFB1 | ADAM19 | 0.073 | bioplex3_WMM WMM_only |
Related Complexes