hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10361.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BMPR2 | Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) | 5 | UniProt NCBI |
| LRRIQ1 | Leucine-rich repeat and IQ domain-containing protein 1 | 3 | UniProt NCBI |
| ACVR1 | Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04350 | 0.0028446957576 | 0.666666666667 | BMPR2 ACVR1 | TGF-beta signaling pathway |
| KEGG:05418 | 0.00515305589505 | 0.666666666667 | BMPR2 ACVR1 | Fluid shear stress and atherosclerosis |
| KEGG:04550 | 0.00542112539104 | 0.666666666667 | BMPR2 ACVR1 | Signaling pathways regulating pluripotency of stem cells |
| WP:WP3931 | 0.00558201247738 | 0.666666666667 | BMPR2 ACVR1 | Embryonic stem cell pluripotency pathways |
| WP:WP2857 | 0.00901139826353 | 0.666666666667 | BMPR2 ACVR1 | Mesodermal commitment pathway |
| KEGG:04060 | 0.0146065267115 | 0.666666666667 | BMPR2 ACVR1 | Cytokine-cytokine receptor interaction |
| GO:0098821 | 0.0210651876021 | 0.666666666667 | BMPR2 ACVR1 | BMP receptor activity |
| GO:0017002 | 0.0393180950424 | 0.666666666667 | BMPR2 ACVR1 | activin receptor activity |
| GO:0003174 | 0.0393180950424 | 0.666666666667 | BMPR2 ACVR1 | mitral valve development |
| GO:0003183 | 0.0393180950424 | 0.666666666667 | BMPR2 ACVR1 | mitral valve morphogenesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| BMPR2 | ACVR1 | 0.988 | 0.176 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| LRRIQ1 | ACVR1 | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LRRIQ1 | BMPR2 | 0.981 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes