hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10364.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| USP10 | Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) | 5 | UniProt NCBI |
| CAPRIN1 | Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105) | 5 | UniProt NCBI |
| PRRC2A | Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2) | 5 | UniProt NCBI |
| G3BP1 | Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0062028 | 3.84440695359e-06 | 0.75 | USP10 G3BP1 CAPRIN1 | regulation of stress granule assembly |
| GO:0034063 | 0.000998468305694 | 0.75 | USP10 G3BP1 CAPRIN1 | stress granule assembly |
| GO:0062029 | 0.0168521501606 | 0.5 | CAPRIN1 G3BP1 | positive regulation of stress granule assembly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| G3BP1 | USP10 | 1.0 | 0.662 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| CAPRIN1 | USP10 | 0.989 | 0.48 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
| CAPRIN1 | G3BP1 | 0.988 | 0.84 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| PRRC2A | G3BP1 | 0.967 | 0.216 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| PRRC2A | USP10 | 0.722 | 0.266 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM treiber_WMM WMM_only |
| PRRC2A | CAPRIN1 | 0.586 | 0.284 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
Related Complexes