hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10368.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZFP36L2 | mRNA decay activator protein ZFP36L2 (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (TPA-induced sequence 11d) (Zinc finger protein 36, C3H1 type-like 2) (ZFP36-like 2) | 5 | UniProt NCBI |
| LPIN1 | Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1) | 5 | UniProt NCBI |
| LPIN3 | Phosphatidate phosphatase LPIN3 (EC 3.1.3.4) (Lipin-3) (Lipin-3-like) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5275 | 0.000153947718176 | 0.666666666667 | LPIN1 LPIN3 | Ether lipid biosynthesis |
| WP:WP5101 | 0.000173183276299 | 0.666666666667 | LPIN1 LPIN3 | Congenital generalized lipodystrophy |
| REAC:R-HSA-1483213 | 0.000374861161166 | 0.666666666667 | LPIN1 LPIN3 | Synthesis of PE |
| REAC:R-HSA-75109 | 0.000449812862905 | 0.666666666667 | LPIN1 LPIN3 | Triglyceride biosynthesis |
| REAC:R-HSA-4419969 | 0.000531572756485 | 0.666666666667 | LPIN1 LPIN3 | Depolymerization of the Nuclear Lamina |
| KEGG:00561 | 0.00104947736992 | 0.666666666667 | LPIN1 LPIN3 | Glycerolipid metabolism |
| REAC:R-HSA-1483191 | 0.00172341693863 | 0.666666666667 | LPIN1 LPIN3 | Synthesis of PC |
| KEGG:00564 | 0.00234368320776 | 0.666666666667 | LPIN1 LPIN3 | Glycerophospholipid metabolism |
| REAC:R-HSA-8979227 | 0.0033773260227 | 0.666666666667 | LPIN1 LPIN3 | Triglyceride metabolism |
| KEGG:04936 | 0.00578906402762 | 0.666666666667 | LPIN1 LPIN3 | Alcoholic liver disease |
| WP:WP236 | 0.0063930178049 | 0.666666666667 | LPIN1 LPIN3 | Adipogenesis |
| REAC:R-HSA-2980766 | 0.00735562020533 | 0.666666666667 | LPIN1 LPIN3 | Nuclear Envelope Breakdown |
| KEGG:04150 | 0.00824863650471 | 0.666666666667 | LPIN1 LPIN3 | mTOR signaling pathway |
| REAC:R-HSA-1483206 | 0.037053837229 | 0.666666666667 | LPIN1 LPIN3 | Glycerophospholipid biosynthesis |
| CORUM:6090 | 0.0499402709677 | 0.333333333333 | LPIN1 | Seipin-lipin1 complex |
| CORUM:7340 | 0.0499402709677 | 0.333333333333 | ZFP36L2 | HNRNPD(p45)-ZFP36L2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LPIN3 | LPIN1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| ZFP36L2 | LPIN1 | 0.95 | 0.104 | hein_WMM bioplex3_WMM WMM_only boldt_WMM |
| LPIN3 | ZFP36L2 | 0.133 | bioplex3_WMM boldt boldt_WMM WMM_only |
Related Complexes