hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10382.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GNE | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)] | 5 | UniProt NCBI |
| MAPRE1 | Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1) | 5 | UniProt NCBI |
| MAPRE3 | Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) | 5 | UniProt NCBI |
| GAS2L2 | GAS2-like protein 2 (GAS2-related protein on chromosome 17) (Growth arrest-specific protein 2-like 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0035372 | 0.000139871762976 | 0.75 | MAPRE1 GAS2L2 MAPRE3 | protein localization to microtubule |
| GO:0035371 | 0.000777349058504 | 0.75 | MAPRE1 GAS2L2 MAPRE3 | microtubule plus-end |
| GO:1990752 | 0.00229706847948 | 0.75 | MAPRE1 GAS2L2 MAPRE3 | microtubule end |
| GO:0072698 | 0.00440499676786 | 0.75 | MAPRE1 GAS2L2 MAPRE3 | protein localization to microtubule cytoskeleton |
| GO:0044380 | 0.00508133939815 | 0.75 | MAPRE1 GAS2L2 MAPRE3 | protein localization to cytoskeleton |
| GO:1905721 | 0.00842684400117 | 0.5 | MAPRE1 MAPRE3 | mitotic spindle astral microtubule end |
| GO:0031110 | 0.0291371139957 | 0.75 | MAPRE1 GAS2L2 MAPRE3 | regulation of microtubule polymerization or depolymerization |
| GO:0061673 | 0.042122686785 | 0.5 | MAPRE1 MAPRE3 | mitotic spindle astral microtubule |
| REAC:R-HSA-4085011 | 0.0499436884912 | 0.25 | GNE | Defective GNE causes sialuria, NK and IBM2 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MAPRE1 | MAPRE3 | 1.0 | 0.076 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM |
| GAS2L2 | MAPRE3 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GNE | GAS2L2 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GAS2L2 | MAPRE1 | 0.991 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GNE | MAPRE3 | 0.476 | 0.064 | bioplex3_WMM WMM_only |
| GNE | MAPRE1 | 0.357 | 0.146 | bioplex3_WMM WMM_only |
Related Complexes