List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_10399.1

Confidence: Medium High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
HK2	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Hexokinase-B) (Muscle form hexokinase)	5	UniProt   NCBI
CD3G	T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g)	5	UniProt   NCBI
HK1	Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I) (Hexokinase-A)	5	UniProt   NCBI
GCK	Hexokinase-4 (HK4) (EC 2.7.1.1) (Glucokinase) (Hexokinase type IV) (HK IV) (Hexokinase-D)	5	UniProt   NCBI
HK3	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III) (Hexokinase-C)	5	UniProt   NCBI
HKDC1	Hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:00524	6.38621123947e-13	0.8	HK2 HKDC1 GCK HK3	Neomycin, kanamycin and gentamicin biosynthesis
GO:0004340	6.57779757665e-10	0.8	HK2 HKDC1 GCK HK3	glucokinase activity
GO:0004396	6.57779757665e-10	0.8	HK2 HKDC1 GCK HK3	hexokinase activity
GO:0008865	6.57779757665e-10	0.8	HK2 HKDC1 GCK HK3	fructokinase activity
KEGG:00500	1.61394203707e-09	0.8	HK2 HKDC1 GCK HK3	Starch and sucrose metabolism
KEGG:00052	1.90728148797e-09	0.8	HK2 HKDC1 GCK HK3	Galactose metabolism
KEGG:01250	6.67665470342e-09	0.8	HK2 HKDC1 GCK HK3	Biosynthesis of nucleotide sugars
KEGG:04930	1.29091351664e-08	0.8	HK2 HKDC1 GCK HK3	Type II diabetes mellitus
KEGG:00520	1.89885898094e-08	0.8	HK2 HKDC1 GCK HK3	Amino sugar and nucleotide sugar metabolism
GO:0046835	2.76191861336e-08	0.8	HK2 HKDC1 GCK HK3	carbohydrate phosphorylation
KEGG:00010	7.10279402923e-08	0.8	HK2 HKDC1 GCK HK3	Glycolysis / Gluconeogenesis
KEGG:05230	9.75657108053e-08	0.8	HK2 HKDC1 GCK HK3	Central carbon metabolism in cancer
WP:WP5394	1.44800475023e-07	0.6	HK2 GCK HK3	UDP derived sugars synthesis in fibroblasts
REAC:R-HSA-70171	2.88233822895e-07	0.8	HK2 HKDC1 GCK HK3	Glycolysis
KEGG:01200	5.84108444617e-07	0.8	HK2 HKDC1 GCK HK3	Carbon metabolism
GO:0019200	6.36865069892e-07	0.8	HK2 HKDC1 GCK HK3	carbohydrate kinase activity
REAC:R-HSA-70326	6.39162420915e-07	0.8	HK2 HKDC1 GCK HK3	Glucose metabolism
KEGG:04910	1.26993763053e-06	0.8	HK2 HKDC1 GCK HK3	Insulin signaling pathway
GO:0051156	1.396459195e-06	0.8	HK2 HKDC1 GCK HK3	glucose 6-phosphate metabolic process
KEGG:00051	5.56653803159e-06	0.6	HK2 HK3 HKDC1	Fructose and mannose metabolism
KEGG:04973	6.08777503567e-06	0.6	HK2 HK3 HKDC1	Carbohydrate digestion and absorption
WP:WP500	9.34985361286e-06	0.6	HK2 HK3 HKDC1	Glycogen synthesis and degradation
WP:WP534	1.3807096837e-05	0.6	HK2 GCK HK3	Glycolysis and gluconeogenesis
REAC:R-HSA-71387	7.36330282621e-05	0.8	HK2 HKDC1 GCK HK3	Metabolism of carbohydrates
GO:0006096	8.87760174517e-05	0.8	HK2 HKDC1 GCK HK3	glycolytic process
GO:0046032	8.87760174517e-05	0.8	HK2 HKDC1 GCK HK3	ADP catabolic process
GO:0046031	9.44983107329e-05	0.8	HK2 HKDC1 GCK HK3	ADP metabolic process
GO:0009181	0.000100492682129	0.8	HK2 HKDC1 GCK HK3	purine ribonucleoside diphosphate catabolic process
GO:0009137	0.000100492682129	0.8	HK2 HKDC1 GCK HK3	purine nucleoside diphosphate catabolic process
GO:0019364	0.00010676760833	0.8	HK2 HKDC1 GCK HK3	pyridine nucleotide catabolic process
GO:0009179	0.00010676760833	0.8	HK2 HKDC1 GCK HK3	purine ribonucleoside diphosphate metabolic process
GO:0009135	0.000113331695245	0.8	HK2 HKDC1 GCK HK3	purine nucleoside diphosphate metabolic process
GO:0001678	0.000113331695245	0.8	HK2 HKDC1 GCK HK3	intracellular glucose homeostasis
GO:0009191	0.000120193677971	0.8	HK2 HKDC1 GCK HK3	ribonucleoside diphosphate catabolic process
WP:WP5355	0.000122528877875	0.6	HK2 GCK HK3	Metabolic Epileptic Disorders
GO:0072526	0.000127362420754	0.8	HK2 HKDC1 GCK HK3	pyridine-containing compound catabolic process
GO:0009134	0.000134846916955	0.8	HK2 HKDC1 GCK HK3	nucleoside diphosphate catabolic process
KEGG:04066	0.00014493342506	0.6	HK2 HK3 HKDC1	HIF-1 signaling pathway
GO:0009185	0.000168126820122	0.8	HK2 HKDC1 GCK HK3	ribonucleoside diphosphate metabolic process
GO:0009132	0.000207211791955	0.8	HK2 HKDC1 GCK HK3	nucleoside diphosphate metabolic process
GO:0006090	0.000305379790485	0.8	HK2 HKDC1 GCK HK3	pyruvate metabolic process
GO:0009154	0.000365836607157	0.8	HK2 HKDC1 GCK HK3	purine ribonucleotide catabolic process
GO:0009261	0.000399224932149	0.8	HK2 HKDC1 GCK HK3	ribonucleotide catabolic process
GO:0006195	0.000472796969853	0.8	HK2 HKDC1 GCK HK3	purine nucleotide catabolic process
GO:0061718	0.000537554131189	0.6	HK2 GCK HK3	glucose catabolic process to pyruvate
GO:0061621	0.000537554131189	0.6	HK2 GCK HK3	canonical glycolysis
GO:0006735	0.000537554131189	0.6	HK2 GCK HK3	NADH regeneration
GO:0072523	0.000556087531591	0.8	HK2 HKDC1 GCK HK3	purine-containing compound catabolic process
GO:0016052	0.000601631697955	0.8	HK2 HKDC1 GCK HK3	carbohydrate catabolic process
GO:0006006	0.000625424261446	0.8	HK2 HKDC1 GCK HK3	glucose metabolic process
GO:0061620	0.000652677252708	0.6	HK2 GCK HK3	glycolytic process through glucose-6-phosphate
GO:0061615	0.000652677252708	0.6	HK2 GCK HK3	glycolytic process through fructose-6-phosphate
GO:0019677	0.000783132248318	0.6	HK2 GCK HK3	NAD catabolic process
GO:0042593	0.000872617123619	0.8	HK2 HKDC1 GCK HK3	glucose homeostasis
GO:0009166	0.000904012985399	0.8	HK2 HKDC1 GCK HK3	nucleotide catabolic process
GO:0006007	0.000929874009882	0.6	HK2 GCK HK3	glucose catabolic process
GO:0033500	0.000936247584533	0.8	HK2 HKDC1 GCK HK3	carbohydrate homeostasis
GO:0019362	0.00103813210542	0.8	HK2 HKDC1 GCK HK3	pyridine nucleotide metabolic process
GO:0046496	0.00103813210542	0.8	HK2 HKDC1 GCK HK3	nicotinamide nucleotide metabolic process
GO:1901292	0.00107387059046	0.8	HK2 HKDC1 GCK HK3	nucleoside phosphate catabolic process
GO:0072524	0.00118663084114	0.8	HK2 HKDC1 GCK HK3	pyridine-containing compound metabolic process
GO:0019318	0.00143851496917	0.8	HK2 HKDC1 GCK HK3	hexose metabolic process
KEGG:05131	0.00175429069912	0.6	HK2 HK3 HKDC1	Shigellosis
GO:0005996	0.00200179443266	0.8	HK2 HKDC1 GCK HK3	monosaccharide metabolic process
GO:0006734	0.00220577099344	0.6	HK2 GCK HK3	NADH metabolic process
GO:0019320	0.00350285844735	0.6	HK2 GCK HK3	hexose catabolic process
GO:0046434	0.00360584954209	0.8	HK2 HKDC1 GCK HK3	organophosphate catabolic process
GO:0046034	0.00388246947083	0.8	HK2 HKDC1 GCK HK3	ATP metabolic process
GO:0046365	0.00430818612204	0.6	HK2 GCK HK3	monosaccharide catabolic process
GO:0009205	0.00515066005871	0.8	HK2 HKDC1 GCK HK3	purine ribonucleoside triphosphate metabolic process
GO:0009144	0.00538890600265	0.8	HK2 HKDC1 GCK HK3	purine nucleoside triphosphate metabolic process
GO:0009199	0.00589005230723	0.8	HK2 HKDC1 GCK HK3	ribonucleoside triphosphate metabolic process
GO:1901136	0.00602060942924	0.8	HK2 HKDC1 GCK HK3	carbohydrate derivative catabolic process
GO:0009141	0.00685002760202	0.8	HK2 HKDC1 GCK HK3	nucleoside triphosphate metabolic process
KEGG:01100	0.0139298332568	0.8	HK2 HKDC1 GCK HK3	Metabolic pathways
GO:0019674	0.0145266888919	0.6	HK2 GCK HK3	NAD metabolic process
WP:WP4018	0.0161598479529	0.4	HK2 HK3	Clear cell renal cell carcinoma pathways
GO:0005975	0.0494529381498	0.8	HK2 HKDC1 GCK HK3	carbohydrate metabolic process



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
HK2	HK1	0.999	0.306	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     boldt     youn_WMM     boldt_WMM
HK3	HK2	0.998	0.132	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
GCK	HK3	0.997		bioplex3_WMM     bioplex3_HCT116     WMM_only
HK3	HK1	0.996	0.036	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
HK1	HKDC1	0.992	0.894	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
CD3G	HKDC1	0.981		bioplex3_WMM     bioplex3_HCT116     WMM_only
HK3	HKDC1	0.962	0.082	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
CD3G	HK1	0.869		bioplex3_WMM     bioplex3_HCT116     WMM_only
GCK	HKDC1	0.427		bioplex3_WMM     WMM_only
GCK	HK2	0.12		bioplex3_WMM     WMM_only
GCK	HK1	0.116		bioplex3_WMM     WMM_only
HK2	HKDC1	0.108	0.13	bioplex_WMM     bioplex3_WMM     WMM_only
HK2	CD3G	0.018		bioplex3_WMM     bioplex3_HCT116     WMM_only





Related Complexes

Genename	Complexes
HK2	huMAP3_02064.1 huMAP3_02978.1 huMAP3_06095.1 huMAP3_06698.1 huMAP3_08681.1 huMAP3_08804.1 huMAP3_09730.1 huMAP3_10023.1 huMAP3_10399.1 huMAP3_10665.1 huMAP3_15292.1
CD3G	huMAP3_02841.1 huMAP3_03913.1 huMAP3_10399.1 huMAP3_11415.1 huMAP3_15292.1
HK1	huMAP3_02978.1 huMAP3_08804.1 huMAP3_10399.1 huMAP3_11415.1 huMAP3_15292.1
GCK	huMAP3_00687.1 huMAP3_02978.1 huMAP3_06698.1 huMAP3_10399.1 huMAP3_14554.1 huMAP3_15292.1
HK3	huMAP3_00687.1 huMAP3_02064.1 huMAP3_02978.1 huMAP3_06698.1 huMAP3_10023.1 huMAP3_10399.1 huMAP3_14554.1 huMAP3_15292.1
HKDC1	huMAP3_03913.1 huMAP3_10399.1 huMAP3_11415.1 huMAP3_15292.1