hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10404.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAPK1 | Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) | 5 | UniProt NCBI |
| PTPRR | Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1) | 5 | UniProt NCBI |
| SUSD4 | Sushi domain-containing protein 4 | 5 | UniProt NCBI |
| MAPK3 | Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1) | 5 | UniProt NCBI |
| DHPS | Deoxyhypusine synthase (DHS) (EC 2.5.1.46) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6801 | 0.0249718442456 | 0.25 | MAPK3 | VEGFR2-S1PR3-ERK1/2-PKC-alpha complex |
| CORUM:55 | 0.049938562206 | 0.25 | MAPK3 | HDAC4-ERK1 complex |
| CORUM:6799 | 0.049938562206 | 0.25 | MAPK3 | VEGFR2-S1PR1-ERK1/2-PKC-alpha complex |
| CORUM:6800 | 0.049938562206 | 0.25 | MAPK3 | VEGFR2-S1PR2-ERK1/2-PKC-alpha complex |
| CORUM:6802 | 0.049938562206 | 0.25 | MAPK3 | VEGFR2-S1PR5-ERK1/2-PKC-alpha complex |
| CORUM:7504 | 0.049938562206 | 0.25 | MAPK3 | CD44-ERK1-ERK2-RHAMM complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MAPK1 | MAPK3 | 0.999 | 0.446 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM |
| DHPS | MAPK1 | 0.998 | 0.024 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| SUSD4 | DHPS | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| DHPS | MAPK3 | 0.985 | 0.022 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| MAPK1 | PTPRR | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PTPRR | MAPK3 | 0.162 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes