hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10416.1
Complex Portal: CPX-15323
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DDX5 | Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) | 5 | UniProt NCBI |
| C19orf53 | Leydig cell tumor 10 kDa protein homolog | 2 | UniProt NCBI |
| DDX17 | Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72) | 5 | UniProt NCBI |
| TMEM270 | Transmembrane protein 270 (Williams-Beuren syndrome chromosomal region 28 protein) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3082 | 0.000230514481314 | 0.5 | DDX5 DDX17 | DGCR8 multiprotein complex |
| CORUM:1332 | 0.000972395234625 | 0.5 | DDX5 DDX17 | Large Drosha complex |
| REAC:R-HSA-3899300 | 0.00718390333861 | 0.5 | DDX5 DDX17 | SUMOylation of transcription cofactors |
| CORUM:351 | 0.047170241778 | 0.5 | DDX5 DDX17 | Spliceosome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DDX5 | DDX17 | 0.999 | 0.6 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM treiber_WMM | |
| TMEM270 | C19orf53 | 0.975 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DDX5 | C19orf53 | 0.957 | 0.14 | hein_WMM bioplex3_WMM WMM_only | |
| C19orf53 | DDX17 | 0.019 | 0.084 | bioplex3_WMM WMM_only | |
| DDX5 | TMEM270 | 0.002 | bioplex3_HEK293 bioplex () bioplex3_HCT116 | ||
| TMEM270 | DDX17 | 0.002 | bioplex3_HEK293 bioplex () bioplex3_HCT116 |
Related Complexes