hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10419.1
Complex Portal: CPX-15229
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CAPN6 | Calpain-6 (Calpain-like protease X-linked) (Calpamodulin) (CalpM) | 5 | UniProt NCBI |
| BAZ1A | Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1) | 5 | UniProt NCBI |
| SYNE2 | Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2) | 5 | UniProt NCBI |
| SUN1 | SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4535 | 0.00178944501344 | 0.5 | SYNE2 SUN1 | Envelope proteins and their potential roles in EDMD physiopathology |
| GO:0140444 | 0.0168521501606 | 0.5 | SYNE2 SUN1 | cytoskeleton-nuclear membrane anchor activity |
| REAC:R-HSA-1221632 | 0.019281632575 | 0.5 | SYNE2 SUN1 | Meiotic synapsis |
| REAC:R-HSA-1500620 | 0.0492961191682 | 0.5 | SYNE2 SUN1 | Meiosis |
| CORUM:94 | 0.049938562206 | 0.25 | BAZ1A | SNF2H-BAZ1A complex |
| CORUM:925 | 0.049938562206 | 0.25 | BAZ1A | SNF2H-BAZ1A complex |
| CORUM:6683 | 0.049938562206 | 0.25 | SYNE2 | SYNE2-TMEM67 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CAPN6 | BAZ1A | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CAPN6 | SYNE2 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CAPN6 | SUN1 | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SYNE2 | SUN1 | 0.374 | 0.166 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| BAZ1A | SUN1 | 0.111 | 0.076 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| BAZ1A | SYNE2 | 0.102 | 0.088 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes