hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10428.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RNF170 | E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (Putative LAG1-interacting protein) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170) | 5 | UniProt NCBI |
| S1PR1 | Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363) | 5 | UniProt NCBI |
| COX16 | Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (hCOX16) | 4 | UniProt NCBI |
| TTYH2 | Protein tweety homolog 2 (hTTY2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5411 | 0.0249718442456 | 0.25 | S1PR1 | HTR1D-S1PR1 complex |
| CORUM:5422 | 0.0249718442456 | 0.25 | S1PR1 | HTR1A-S1PR1 complex |
| CORUM:6798 | 0.049938562206 | 0.25 | S1PR1 | S1PR1-c-Met-ITGB4 complex, HGF- or S1P-induced |
| CORUM:6799 | 0.049938562206 | 0.25 | S1PR1 | VEGFR2-S1PR1-ERK1/2-PKC-alpha complex |
| CORUM:6805 | 0.049938562206 | 0.25 | S1PR1 | S1PR1-beta-arrestin 2 complex, ApoM(+)HDL-S1P stimulated |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TTYH2 | S1PR1 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| COX16 | S1PR1 | 0.981 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| S1PR1 | RNF170 | 0.962 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TTYH2 | RNF170 | 0.464 | 0.134 | bioplex3_WMM WMM_only |
| COX16 | RNF170 | 0.46 | 0.06 | bioplex3_WMM WMM_only |
| COX16 | TTYH2 | 0.302 | 0.088 | bioplex3_WMM WMM_only |
Related Complexes