hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10429.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MTERF4 | Transcription termination factor 4, mitochondrial (Mitochondrial transcription termination factor 4) (mTERF domain-containing protein 2) [Cleaved into: mTERF domain-containing protein 2 processed] | 5 | UniProt NCBI |
| NSUN4 | 5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (5-methylcytosine tRNA methyltransferase NSUN4) (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4) | 5 | UniProt NCBI |
| MYEF2 | Myelin expression factor 2 (MEF-2) (MyEF-2) (MST156) | 5 | UniProt NCBI |
| MND1 | Meiotic nuclear division protein 1 homolog | 3 | UniProt NCBI |
| PSMC3IP | Homologous-pairing protein 2 homolog (Nuclear receptor coactivator GT198) (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein) (Tat-binding protein 1-interacting protein) (TBP-1-interacting protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:254 | 1.36501667663e-05 | 0.4 | MND1 PSMC3IP | TBPIP/HOP2-MND1 complex |
| REAC:R-HSA-6793080 | 0.000227895019208 | 0.4 | NSUN4 MTERF4 | rRNA modification in the mitochondrion |
| REAC:R-HSA-8868766 | 0.000683310775372 | 0.4 | NSUN4 MTERF4 | rRNA processing in the mitochondrion |
| REAC:R-HSA-912446 | 0.0384836492499 | 0.4 | MND1 PSMC3IP | Meiotic recombination |
| WP:WP5316 | 0.0477224874935 | 0.4 | MND1 PSMC3IP | Primary ovarian insufficiency |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MND1 | PSMC3IP | 0.999 | 0.154 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 fraction |
| MTERF4 | MND1 | 0.986 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| NSUN4 | MND1 | 0.981 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| NSUN4 | MTERF4 | 0.979 | 0.35 | bioplex_WMM bioplex3_WMM WMM_only |
| NSUN4 | MYEF2 | 0.97 | 0.024 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| MTERF4 | PSMC3IP | 0.172 | 0.146 | bioplex_WMM bioplex3_WMM WMM_only |
| NSUN4 | PSMC3IP | 0.159 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only |
| MYEF2 | MTERF4 | 0.059 | 0.05 | bioplex3_WMM WMM_only |
Related Complexes