hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10430.1

Confidence: Medium High

Show entries

Search:

Genename	Protein Name	Uniprot Annotation Score	Links
ACVR1	Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)	5	UniProt NCBI
BMPR2	Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)	5	UniProt NCBI
FKBP1B	Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)	5	UniProt NCBI
KCNK18	Potassium channel subfamily K member 18 (TWIK-related individual potassium channel) (TWIK-related spinal cord potassium channel)	5	UniProt NCBI
LRRIQ1	Leucine-rich repeat and IQ domain-containing protein 1	3	UniProt NCBI
SLC8A1	Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)	5	UniProt NCBI
TMEM204	Transmembrane protein 204 (Claudin-like protein 24)	4	UniProt NCBI
UNC5B	Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1)	5	UniProt NCBI

Showing 1 to 8 of 8 entries

Show entries

Search:

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-5576891	0.00221515749645	0.375	FKBP1B SLC8A1 KCNK18	Cardiac conduction
REAC:R-HSA-397014	0.012158802958	0.375	FKBP1B SLC8A1 KCNK18	Muscle contraction
GO:0030501	0.0217028525661	0.375	ACVR1 SLC8A1 BMPR2	positive regulation of bone mineralization
GO:0045778	0.0319547930493	0.375	ACVR1 SLC8A1 BMPR2	positive regulation of ossification
GO:0070169	0.0381082872278	0.375	ACVR1 SLC8A1 BMPR2	positive regulation of biomineral tissue development
REAC:R-HSA-5578775	0.0452582424141	0.25	SLC8A1 FKBP1B	Ion homeostasis
KEGG:04350	0.0474398326563	0.25	ACVR1 BMPR2	TGF-beta signaling pathway

Showing 1 to 7 of 7 entries

Show entries

Search:

Protein 1	Protein 2	Score	ProteomeHD	Evidence
ACVR1	TMEM204	0.993		bioplex3_WMM bioplex3_HCT116 WMM_only
ACVR1	FKBP1B	0.989	0.046	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ACVR1	SLC8A1	0.989	0.052	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
BMPR2	ACVR1	0.988	0.176	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
LRRIQ1	ACVR1	0.984		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
LRRIQ1	UNC5B	0.982		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
LRRIQ1	BMPR2	0.981		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ACVR1	KCNK18	0.981		bioplex3_HEK293 bioplex3_WMM WMM_only
SLC8A1	FKBP1B	0.557	0.06	bioplex_WMM bioplex3_WMM WMM_only
UNC5B	ACVR1	0.492	0.17	bioplex_WMM bioplex3_WMM WMM_only

Showing 1 to 10 of 13 entries

Related Complexes

Genename	Complexes
TMEM204	huMAP3_02078.1 huMAP3_03006.1 huMAP3_03859.1 huMAP3_04994.1 huMAP3_05434.1 huMAP3_05550.1 huMAP3_07383.1 huMAP3_08579.1 huMAP3_09144.1 huMAP3_09749.1 huMAP3_09880.1 huMAP3_10430.1 huMAP3_10877.1 huMAP3_11072.1 huMAP3_11149.1 huMAP3_13675.1
SLC8A1	huMAP3_02078.1 huMAP3_04994.1 huMAP3_05550.1 huMAP3_07383.1 huMAP3_08579.1 huMAP3_08683.1 huMAP3_09144.1 huMAP3_09491.1 huMAP3_09880.1 huMAP3_10430.1 huMAP3_10877.1 huMAP3_13675.1 huMAP3_13758.1
KCNK18	huMAP3_02078.1 huMAP3_04994.1 huMAP3_05550.1 huMAP3_07383.1 huMAP3_08579.1 huMAP3_08683.1 huMAP3_09144.1 huMAP3_09491.1 huMAP3_09880.1 huMAP3_10430.1 huMAP3_10877.1 huMAP3_12317.1 huMAP3_13758.1 huMAP3_14048.1 huMAP3_15212.1
LRRIQ1	huMAP3_00217.1 huMAP3_05550.1 huMAP3_06103.1 huMAP3_08579.1 huMAP3_08682.1 huMAP3_09144.1 huMAP3_10361.1 huMAP3_10430.1 huMAP3_11581.1 huMAP3_11605.1 huMAP3_12979.1 huMAP3_13758.1
ACVR1	huMAP3_01259.1 huMAP3_02078.1 huMAP3_04994.1 huMAP3_05550.1 huMAP3_06211.1 huMAP3_07383.1 huMAP3_08579.1 huMAP3_08683.1 huMAP3_09144.1 huMAP3_09491.1 huMAP3_09880.1 huMAP3_10361.1 huMAP3_10430.1 huMAP3_10877.1 huMAP3_13675.1 huMAP3_13758.1
BMPR2	huMAP3_01259.1 huMAP3_02566.1 huMAP3_05550.1 huMAP3_06103.1 huMAP3_07718.1 huMAP3_09491.1 huMAP3_09880.1 huMAP3_10361.1 huMAP3_10430.1 huMAP3_13675.1 huMAP3_14293.1 huMAP3_14903.1 huMAP3_14998.1
UNC5B	huMAP3_00217.1 huMAP3_02333.1 huMAP3_06103.1 huMAP3_06114.1 huMAP3_06717.1 huMAP3_08682.1 huMAP3_10430.1 huMAP3_11273.1 huMAP3_11581.1 huMAP3_13902.1 huMAP3_14949.1 huMAP3_15094.1
FKBP1B	huMAP3_02078.1 huMAP3_04994.1 huMAP3_05550.1 huMAP3_07383.1 huMAP3_08579.1 huMAP3_08683.1 huMAP3_09144.1 huMAP3_09491.1 huMAP3_09880.1 huMAP3_10430.1 huMAP3_10877.1 huMAP3_13675.1 huMAP3_13758.1