hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10446.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OAT | Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine delta-aminotransferase) (Ornithine--oxo-acid aminotransferase) [Cleaved into: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form] | 5 | UniProt NCBI |
| COQ9 | Ubiquinone biosynthesis protein COQ9, mitochondrial | 5 | UniProt NCBI |
| GPT2 | Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) | 5 | UniProt NCBI |
| THEM5 | Acyl-coenzyme A thioesterase THEM5 (Acyl-CoA thioesterase THEM5) (EC 3.1.2.2) (Acyl-coenzyme A thioesterase 15) (Thioesterase superfamily member 5) | 5 | UniProt NCBI |
| GPT | Alanine aminotransferase 1 (ALT1) (EC 2.6.1.2) (Glutamate pyruvate transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1) (Glutamic--pyruvic transaminase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00220 | 0.000775497043052 | 0.4 | GPT2 GPT | Arginine biosynthesis |
| GO:0008483 | 0.000783132248318 | 0.6 | GPT2 OAT GPT | transaminase activity |
| GO:0016769 | 0.000929874009882 | 0.6 | GPT2 OAT GPT | transferase activity, transferring nitrogenous groups |
| WP:WP4595 | 0.0011148137474 | 0.4 | GPT OAT | Urea cycle and associated pathways |
| KEGG:01210 | 0.00196978543336 | 0.4 | GPT2 GPT | 2-Oxocarboxylic acid metabolism |
| KEGG:00250 | 0.00210534424221 | 0.4 | GPT2 GPT | Alanine, aspartate and glutamate metabolism |
| GO:0004021 | 0.00468200720083 | 0.4 | GPT2 GPT | L-alanine:2-oxoglutarate aminotransferase activity |
| GO:0047635 | 0.00468200720083 | 0.4 | GPT2 GPT | alanine-oxo-acid transaminase activity |
| KEGG:01230 | 0.00996128881886 | 0.4 | GPT2 GPT | Biosynthesis of amino acids |
| WP:WP3925 | 0.0197951791935 | 0.4 | GPT2 OAT | Amino acid metabolism |
| KEGG:01200 | 0.024008315736 | 0.4 | GPT2 GPT | Carbon metabolism |
| HPA:0271142 | 0.0324319514824 | 0.6 | GPT OAT COQ9 | kidney; proximal tubules (cell body)[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GPT2 | THEM5 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GPT2 | GPT | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| COQ9 | THEM5 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| OAT | THEM5 | 0.991 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| COQ9 | GPT2 | 0.418 | 0.042 | bioplex3_WMM WMM_only |
| COQ9 | OAT | 0.229 | 0.088 | bioplex3_WMM WMM_only |
| GPT2 | OAT | 0.136 | 0.22 | bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only |
| GPT | OAT | 0.011 | 0.167333333333 | bioplex3_WMM WMM_only |
Related Complexes