hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10453.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CDC34 | Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1) | 5 | UniProt NCBI |
| UBE2R2 | Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2) | 5 | UniProt NCBI |
| TCEANC2 | Transcription elongation factor A N-terminal and central domain-containing protein 2 | 3 | UniProt NCBI |
| WDR70 | WD repeat-containing protein 70 | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8866652 | 0.00444848198459 | 0.5 | CDC34 UBE2R2 | Synthesis of active ubiquitin: roles of E1 and E2 enzymes |
| KEGG:04120 | 0.0224124539322 | 0.5 | CDC34 UBE2R2 | Ubiquitin mediated proteolysis |
| REAC:R-HSA-8852135 | 0.0275106007785 | 0.5 | CDC34 UBE2R2 | Protein ubiquitination |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UBE2R2 | CDC34 | 0.999 | 0.186 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| TCEANC2 | WDR70 | 0.976 | 0.16 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CDC34 | TCEANC2 | 0.975 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| UBE2R2 | TCEANC2 | 0.965 | 0.134 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CDC34 | WDR70 | 0.262 | 0.092 | bioplex_WMM bioplex3_WMM WMM_only |
| UBE2R2 | WDR70 | 0.187 | 0.07 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes