hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10488.1
Complex Portal: CPX-21425
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GTSF1 | Gametocyte-specific factor 1 (Protein FAM112B) | 3 | UniProt NCBI |
| RIC1 | Guanine nucleotide exchange factor subunit RIC1 (Connexin-43-interacting protein of 150 kDa) (Protein RIC1 homolog) (RAB6A-GEF complex partner protein 1) | 5 | UniProt NCBI |
| ETNK2 | Ethanolamine kinase 2 (EKI 2) (EC 2.7.1.82) (Ethanolamine kinase-like protein) | 5 | UniProt NCBI |
| RGP1 | RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog) | 5 | UniProt NCBI |
| SOCS3 | Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0034066 | 0.00468200720083 | 0.4 | RIC1 RGP1 | Ric1-Rgp1 guanyl-nucleotide exchange factor complex |
| REAC:R-HSA-6811438 | 0.0142979612853 | 0.4 | RIC1 RGP1 | Intra-Golgi traffic |
| REAC:R-HSA-6811440 | 0.0163316506439 | 0.4 | RIC1 RGP1 | Retrograde transport at the Trans-Golgi-Network |
| HPA:0211092 | 0.0402929100991 | 0.6 | RGP1 ETNK2 SOCS3 | fallopian tube; non-ciliated cells[>=Medium] |
| REAC:R-HSA-8876198 | 0.0487218825663 | 0.4 | RIC1 RGP1 | RAB GEFs exchange GTP for GDP on RABs |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RGP1 | ETNK2 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RGP1 | SOCS3 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| RGP1 | GTSF1 | 0.987 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RGP1 | RIC1 | 0.966 | 0.17 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes