hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10503.1
Complex Portal: CPX-13499
Confidence: Medium High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTPRJ | Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148) | 5 | UniProt   NCBI |
| ALCAM | CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166) | 5 | UniProt   NCBI |
| CSF3 | Granulocyte colony-stimulating factor (G-CSF) (Pluripoietin) (Filgrastim) (Lenograstim) | 5 | UniProt   NCBI |
| LGALS8 | Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1) | 5 | UniProt   NCBI |
| KIAA1549 | UPF0606 protein KIAA1549 | 5 | UniProt   NCBI |
| KIAA0319L | Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR) | 5 | UniProt   NCBI |
| PTPRK | Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48) | 5 | UniProt   NCBI |
| ITGB1 | Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29) | 5 | UniProt   NCBI |
| CSPG4 | Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan) | 5 | UniProt   NCBI |
| PLA2G2E | Group IIE secretory phospholipase A2 (GIIE sPLA2) (sPLA2-IIE) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 2E) | 5 | UniProt   NCBI |
| PODXL | Podocalyxin (GCTM-2 antigen) (Gp200) (Podocalyxin-like protein 1) (PC) (PCLP-1) | 5 | UniProt   NCBI |
| ITGA2 | Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b) | 5 | UniProt   NCBI |
| CD276 | CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276) | 5 | UniProt   NCBI |
| ITGA5 | Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain] | 5 | UniProt   NCBI |
| FLT4 | Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4) | 5 | UniProt   NCBI |
| PTPRG | Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48) | 5 | UniProt   NCBI |
| HEG1 | Protein HEG homolog 1 | 5 | UniProt   NCBI |
| ITGA3 | Integrin alpha-3 (CD49 antigen-like family member C) (FRP-2) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain] | 5 | UniProt   NCBI |
| NECTIN1 | Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111) | 5 | UniProt   NCBI |
| SDK1 | Protein sidekick-1 | 5 | UniProt   NCBI |
| MRC2 | C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280) | 5 | UniProt   NCBI |
| LNPEP | Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form] | 5 | UniProt   NCBI |
| PTGFRN | Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315) | 5 | UniProt   NCBI |
| ITGA1 | Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a) | 5 | UniProt   NCBI |
| ITGA8 | Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain] | 5 | UniProt   NCBI |
| LGALS3 | Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen) | 5 | UniProt   NCBI |
| ENPP4 | Bis(5'-adenosyl)-triphosphatase ENPP4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   CORUM:6951 | 2.62090379737e-10 | 0.16 | ITGB1 ITGA3 LGALS3 CSPG4 | NG2-galectin-3-alpha3beta1-integrin complex |
|   GO:0070161 | 1.83084013266e-07 | 0.52 | ITGB1 MRC2 ITGA5 PTPRK ITGA8 CSPG4 PODXL NECTIN1 ITGA3 ALCAM ITGA1 PTPRJ HEG1 | anchoring junction |
|   GO:0098609 | 1.26943401033e-06 | 0.48 | CD276 ITGB1 SDK1 ITGA8 ITGA5 PODXL NECTIN1 ITGA3 ALCAM ITGA1 LGALS3 PLA2G2E | cell-cell adhesion |
|   WP:WP4541 | 1.32940878704e-06 | 0.24 | ITGB1 ITGA5 ITGA8 ITGA1 ITGA3 FLT4 | Hippo Merlin signaling dysregulation |
|   GO:0007155 | 1.54780822285e-06 | 0.56 | ITGB1 ITGA8 CD276 PTPRK SDK1 ITGA5 PLA2G2E NECTIN1 ITGA3 ALCAM ITGA1 PTPRJ LGALS3 PODXL | cell adhesion |
|   GO:0008305 | 4.03857667689e-06 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | integrin complex |
|   WP:WP2118 | 5.45232287585e-06 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Arrhythmogenic right ventricular cardiomyopathy |
|   KEGG:04512 | 5.56116935053e-06 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | ECM-receptor interaction |
|   KEGG:05412 | 5.99567356952e-06 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Arrhythmogenic right ventricular cardiomyopathy |
|   KEGG:05410 | 1.05294684342e-05 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Hypertrophic cardiomyopathy |
|   KEGG:05414 | 1.05294684342e-05 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Dilated cardiomyopathy |
|   GO:0033627 | 1.4266312665e-05 | 0.24 | ITGB1 ITGA5 ITGA8 ITGA1 PODXL ITGA3 | cell adhesion mediated by integrin |
|   GO:0009986 | 1.47736742505e-05 | 0.44 | ITGB1 CD276 PTPRK ITGA8 ITGA5 CSPG4 ITGA3 ITGA1 PTPRJ LGALS3 PTGFRN | cell surface |
|   REAC:R-HSA-216083 | 2.04354858576e-05 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Integrin cell surface interactions |
|   KEGG:04151 | 2.34456069883e-05 | 0.28 | CSF3 ITGA5 ITGA8 ITGA1 ITGA3 ITGB1 FLT4 | PI3K-Akt signaling pathway |
|   KEGG:04510 | 2.39428252941e-05 | 0.24 | ITGB1 ITGA5 ITGA8 ITGA1 ITGA3 FLT4 | Focal adhesion |
|   WP:WP4172 | 3.05065100126e-05 | 0.28 | CSF3 ITGA5 ITGA8 ITGA1 ITGA3 ITGB1 FLT4 | PI3K Akt signaling pathway |
|   WP:WP185 | 3.2674456701e-05 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Integrin mediated cell adhesion |
|   GO:0030054 | 3.38142584388e-05 | 0.56 | ITGB1 MRC2 ITGA8 ITGA5 PTPRK SDK1 CSPG4 PODXL NECTIN1 ITGA3 ALCAM ITGA1 PTPRJ HEG1 | cell junction |
|   KEGG:04514 | 5.07605866429e-05 | 0.2 | ITGA8 ALCAM NECTIN1 CD276 ITGB1 | Cell adhesion molecules |
|   CORUM:2385 | 0.000110598595295 | 0.08 | ITGB1 ITGA5 | ITGA5-ITGB4 complex |
|   CORUM:2435 | 0.000110598595295 | 0.08 | ITGB1 ITGA1 | ITGA1-ITGB1-PTPN2 complex |
|   CORUM:2406 | 0.000110598595295 | 0.08 | ITGB1 ITGA3 | ITGA3-ITGB1 complex |
|   CORUM:2439 | 0.000110598595295 | 0.08 | ITGB1 ITGA8 | ITGA8-ITGB1 complex |
|   CORUM:2401 | 0.000110598595295 | 0.08 | ITGB1 ITGA3 | ITGA3-ITGB1-THBS1 complex |
|   CORUM:3112 | 0.000110598595295 | 0.08 | ITGB1 ITGA5 | ITGA5-ITGB1-SPP1 complex |
|   CORUM:2434 | 0.000110598595295 | 0.08 | ITGB1 ITGA1 | ITGA1-ITGB1-COL6A3 complex |
|   KEGG:04640 | 0.000183720839054 | 0.16 | CSF3 ITGA3 ITGA1 ITGA5 | Hematopoietic cell lineage |
|   GO:0098636 | 0.000201052199296 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | protein complex involved in cell adhesion |
|   GO:0007160 | 0.000257845528861 | 0.28 | ITGB1 ITGA5 PTPRK ITGA8 ITGA1 ITGA3 PTPRJ | cell-matrix adhesion |
|   CORUM:2398 | 0.000331447634556 | 0.08 | ITGB1 ITGA3 | ITGA3-ITGB1-BSG complex |
|   CORUM:2400 | 0.000331447634556 | 0.08 | ITGB1 ITGA3 | ITGA3-ITGB1-CD151 complex |
|   CORUM:2399 | 0.000331447634556 | 0.08 | ITGB1 ITGA3 | ITGA3-ITGB1-CD63 complex |
|   CORUM:2850 | 0.000331447634556 | 0.08 | ITGB1 ITGA5 | ITGA5-ITGB1-FN-1-NOV complex |
|   CORUM:2853 | 0.000331447634556 | 0.08 | ITGB1 ITGA5 | ITGA5-ITGB1-CAL4A3 complex |
|   CORUM:2384 | 0.000331447634556 | 0.08 | ITGB1 ITGA5 | ITGA5-ITGB1-ADAM15 complex |
|   WP:WP3932 | 0.000367619274478 | 0.24 | CSF3 ITGB1 ITGA8 ITGA5 ITGA3 FLT4 | Focal adhesion PI3K Akt mTOR signaling pathway |
|   CORUM:2383 | 0.000662199752723 | 0.08 | ITGB1 ITGA5 | ITGA5-ITGB1-FN1-TGM2 complex |
|   GO:0005178 | 0.000746395792877 | 0.24 | ITGB1 ITGA5 ITGA8 LGALS8 ITGA1 ITGA3 | integrin binding |
|   KEGG:04810 | 0.00110965734558 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Regulation of actin cytoskeleton |
|   WP:WP306 | 0.00116442720428 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Focal adhesion |
|   WP:WP4823 | 0.00309297796921 | 0.12 | ITGB1 ITGA8 ITGA3 | Genes controlling nephrogenesis |
|   GO:0098802 | 0.003246625575 | 0.24 | ITGB1 ITGA1 ITGA8 ITGA5 ITGA3 ALCAM | plasma membrane signaling receptor complex |
|   WP:WP5087 | 0.0037161340439 | 0.24 | CSF3 ITGB1 ITGA1 PODXL ITGA3 FLT4 | Pleural mesothelioma |
|   KEGG:03266 | 0.0037909872345 | 0.08 | ITGA5 NECTIN1 | Virion - Herpesvirus |
|   REAC:R-HSA-3000157 | 0.00408670502449 | 0.12 | ITGB1 ITGA1 ITGA3 | Laminin interactions |
|   GO:0005925 | 0.00413101168996 | 0.32 | ITGB1 MRC2 CSPG4 ITGA8 ITGA5 ITGA3 ALCAM ITGA1 | focal adhesion |
|   GO:0031589 | 0.00424472239425 | 0.28 | ITGB1 ITGA5 PTPRK ITGA8 ITGA1 ITGA3 PTPRJ | cell-substrate adhesion |
|   GO:0030055 | 0.00480356012093 | 0.32 | ITGB1 MRC2 CSPG4 ITGA8 ITGA5 ITGA3 ALCAM ITGA1 | cell-substrate junction |
|   WP:WP4217 | 0.00507278225856 | 0.16 | ITGB1 ITGA3 ITGA1 ITGA5 | Ebola virus infection in host |
|   GO:0005886 | 0.00727029482523 | 0.72 | ITGB1 KIAA1549 ITGA8 CD276 SDK1 LNPEP PTPRK FLT4 CSPG4 ITGA5 PODXL ITGA3 ALCAM ENPP4 ITGA1 PTPRJ LGALS3 NECTIN1 | plasma membrane |
|   KEGG:05165 | 0.00785206819056 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Human papillomavirus infection |
|   GO:0007229 | 0.00814980856806 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | integrin-mediated signaling pathway |
|   REAC:R-HSA-373760 | 0.00820529332776 | 0.16 | ALCAM ITGA5 ITGA1 ITGB1 | L1CAM interactions |
|   REAC:R-HSA-1566977 | 0.00909211447577 | 0.08 | ITGB1 ITGA5 | Fibronectin matrix formation |
|   GO:0005102 | 0.00977731030952 | 0.44 | ITGB1 CD276 ITGA3 LGALS8 ITGA8 ITGA5 CSF3 ALCAM ITGA1 PTPRJ LGALS3 | signaling receptor binding |
|   REAC:R-HSA-1566948 | 0.00987488543448 | 0.12 | ITGB1 ITGA8 ITGA5 | Elastic fibre formation |
|   REAC:R-HSA-1474244 | 0.0118232825819 | 0.2 | ITGB1 ITGA3 ITGA8 ITGA1 ITGA5 | Extracellular matrix organization |
|   GO:0043235 | 0.0161056714975 | 0.28 | ITGB1 ITGA5 ITGA8 ITGA1 ITGA3 ALCAM FLT4 | receptor complex |
|   WP:WP2572 | 0.0189400287423 | 0.12 | ITGB1 PODXL ITGA3 | Primary focal segmental glomerulosclerosis FSGS |
|   REAC:R-HSA-447041 | 0.0190534033734 | 0.08 | ITGB1 ITGA1 | CHL1 interactions |
|   KEGG:04520 | 0.0266167645451 | 0.12 | PTPRJ NECTIN1 HEG1 | Adherens junction |
|   GO:0050839 | 0.0295934475295 | 0.32 | ITGB1 ITGA1 LGALS8 ITGA8 ITGA5 NECTIN1 ITGA3 PTPRJ | cell adhesion molecule binding |
|   GO:0071944 | 0.0347012086389 | 0.72 | ITGB1 KIAA1549 ITGA8 CD276 SDK1 LNPEP PTPRK FLT4 CSPG4 ITGA5 PODXL ITGA3 ALCAM ENPP4 ITGA1 PTPRJ LGALS3 NECTIN1 | cell periphery |
|   REAC:R-HSA-75892 | 0.0407003939962 | 0.08 | ITGB1 ITGA1 | Platelet Adhesion to exposed collagen |
|   GO:0032501 | 0.0485523528532 | 0.76 | KIAA0319L LNPEP MRC2 ITGA8 ITGB1 SDK1 HEG1 ITGA3 LGALS8 FLT4 ITGA5 PLA2G2E CD276 CSF3 ALCAM ENPP4 PTPRJ LGALS3 PODXL | multicellular organismal process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
|  ITGB1 |  ITGA5 | 1.0 | 0.328           |
structurally_consistent (dimer)        
|
|  HEG1 |  LGALS8 | 0.999 | 0.048           |          |
|  LGALS8 |  PTPRJ | 0.999 | 0.016           |          |
|  LGALS8 |  PODXL | 0.999 | 0.038           |          |
|  LGALS3 |  PTPRJ | 0.998 | 0.226           |          |
|  LGALS8 |  CD276 | 0.997 | 0.018           |          |
|  LGALS8 |  PTPRG | 0.997 | 0.048           |          |
|  LGALS8 |  CSPG4 | 0.996 | 0.038           |          |
|  ITGB1 |  ITGA1 | 0.996 | 0.334           |
structurally_consistent (dimer)        
|
|  LGALS8 |  KIAA0319L | 0.996 | 0.044           |          |
|  LGALS3 |  LNPEP | 0.996 | 0.128           |          |
|  LGALS8 |  ITGA5 | 0.996 | 0.038           |          |
|  LGALS3 |  PODXL | 0.995 | 0.09           |          |
|  LGALS8 |  LNPEP | 0.995 | 0.042           |          |
|  ITGA1 |  LGALS8 | 0.994 | 0.058           |          |
|  ITGB1 |  ITGA2 | 0.993 | 0.352           |
structurally_consistent (dimer)        
|
|  LGALS8 |  PTPRK | 0.993 |            |          |
|  LGALS8 |  ALCAM | 0.993 | 0.0555           |          |
|  LGALS8 |  MRC2 | 0.993 | 0.048           |
structurally_consistent (dimer)        
|
|  NECTIN1 |  LGALS8 | 0.991 | 0.054           |          |
|  ITGA3 |  LGALS8 | 0.989 | 0.044           |          |
|  PODXL |  PTPRJ | 0.989 | 0.104           |          |
|  PTPRJ |  ALCAM | 0.989 | 0.152           |          |
|  ITGB1 |  ITGA8 | 0.989 |            |
structurally_consistent (dimer)        
|
|  LGALS3 |  ALCAM | 0.989 | 0.112           |          |
|  KIAA0319L |  PTPRK | 0.988 |            |          |
|  PTPRJ |  CSPG4 | 0.987 | 0.0581538461538           |          |
|  MRC2 |  PTPRK | 0.987 |            |          |
|  KIAA0319L |  PODXL | 0.986 | 0.07           |          |
|  LGALS8 |  PTGFRN | 0.985 | 0.03           |          |
|  PTPRJ |  CSF3 | 0.985 |            |          |
|  CD276 |  KIAA0319L | 0.985 | 0.062           |          |
|  ENPP4 |  LGALS8 | 0.983 | 0.046           |          |
|  LGALS3 |  HEG1 | 0.982 | 0.052           |          |
|  ALCAM |  CSPG4 | 0.981 | 0.086           |          |
|  KIAA0319L |  LNPEP | 0.98 | 0.058           |          |
|  LGALS3 |  CSPG4 | 0.979 | 0.056           |          |
|  ITGB1 |  LGALS8 | 0.979 | 0.048           |          |
|  LGALS8 |  FLT4 | 0.978 | 0.048           |          |
|  LGALS3 |  MRC2 | 0.977 | 0.096           |          |
|  LGALS8 |  KIAA1549 | 0.977 | 0.068           |          |
|  ITGA3 |  ITGA5 | 0.977 | 0.328           |          |
|  ITGA2 |  CSPG4 | 0.977 | 0.134           |          |
|  ENPP4 |  MRC2 | 0.976 | 0.108           |          |
|  HEG1 |  PODXL | 0.975 | 0.038           |          |
|  ENPP4 |  PTPRJ | 0.975 | 0.092           |          |
|  PTPRJ |  LNPEP | 0.971 | 0.118           |          |
|  ITGB1 |  PTPRK | 0.97 |            |          |
|  ALCAM |  MRC2 | 0.97 | 0.096           |          |
|  ITGA1 |  PTPRJ | 0.969 | 0.046           |          |
|  HEG1 |  PTPRK | 0.969 |            |          |
|  HEG1 |  PTPRJ | 0.969 | 0.07           |          |
|  ITGB1 |  ITGA3 | 0.968 | 0.442           |
structurally_consistent (dimer)        
|
|  ITGA3 |  ITGA2 | 0.967 | 0.55           |          |
|  HEG1 |  CSPG4 | 0.967 | 0.068           |          |
|  HEG1 |  ITGA1 | 0.967 | 0.074           |          |
|  HEG1 |  ALCAM | 0.967 | 0.04           |          |
|  CD276 |  PTPRJ | 0.966 | 0.09           |          |
|  ITGA1 |  ITGA5 | 0.966 | 0.144           |          |
|  PTPRG |  PODXL | 0.966 | 0.106           |          |
|  LGALS3 |  PTGFRN | 0.966 | 0.0922222222222           |          |
|  PODXL |  CSPG4 | 0.965 | 0.016           |          |
|  PODXL |  PTPRK | 0.964 |            |          |
|  PTPRJ |  PTGFRN | 0.963 | 0.088           |          |
|  ITGA2 |  ITGA5 | 0.963 | 0.238           |          |
|  MRC2 |  PTGFRN | 0.962 | 0.07           |          |
|  LGALS3 |  KIAA1549 | 0.961 | 0.0943846153846           |          |
|  KIAA0319L |  CSPG4 | 0.961 | 0.066           |          |
|  KIAA0319L |  PTPRJ | 0.961 | 0.044           |          |
|  LGALS3 |  KIAA0319L | 0.96 | 0.036           |          |
|  PTPRJ |  PTPRK | 0.96 |            |          |
|  PTPRJ |  MRC2 | 0.96 | 0.038           |          |
|  ITGA3 |  CSPG4 | 0.959 | 0.098           |          |
|  ITGB1 |  PTPRJ | 0.959 | 0.286           |          |
|  LGALS8 |  SDK1 | 0.959 |            |          |
|  ITGA5 |  PLA2G2E | 0.957 |            |          |
|  ITGA8 |  PTPRK | 0.957 |            |          |
|  ALCAM |  PTGFRN | 0.956 | 0.078           |          |
|  ITGA2 |  LGALS8 | 0.956 | 0.032           |          |
|  NECTIN1 |  ITGA1 | 0.955 | 0.056           |          |
|  HEG1 |  NECTIN1 | 0.954 | 0.052           |          |
|  HEG1 |  MRC2 | 0.954 | 0.124           |          |
|  ALCAM |  PTPRK | 0.954 |            |          |
|  KIAA0319L |  ALCAM | 0.952 | 0.068           |          |
|  ITGA1 |  PTGFRN | 0.952 | 0.118           |          |
|  ITGA1 |  LNPEP | 0.951 | 0.04           |          |
|  ITGA1 |  PTPRK | 0.951 |            |          |
|  ITGA2 |  PTPRJ | 0.95 | 0.224           |          |
|  PTGFRN |  CSPG4 | 0.949 | 0.016           |          |
|  NECTIN1 |  PTPRJ | 0.949 | 0.082           |          |
|  PODXL |  ALCAM | 0.949 | 0.054           |          |
|  ITGA3 |  PTPRK | 0.948 |            |          |
|  ITGA1 |  ALCAM | 0.948 | 0.084           |          |
|  ITGA2 |  ALCAM | 0.948 | 0.174           |          |
|  NECTIN1 |  ITGA5 | 0.947 | 0.11           |          |
|  ITGA1 |  MRC2 | 0.946 | 0.074           |          |
|  PTGFRN |  LNPEP | 0.945 | 0.12           |          |
|  ITGA1 |  KIAA0319L | 0.944 | 0.05           |          |
|  ENPP4 |  ALCAM | 0.94 | 0.074           |          |
|  CSPG4 |  PTPRK | 0.94 |            |          |
|  CD276 |  LNPEP | 0.939 | 0.038           |          |
|  ITGA2 |  PTGFRN | 0.939 | 0.058           |          |
|  ITGB1 |  LNPEP | 0.938 | 0.322           |          |
|  ALCAM |  LNPEP | 0.933 | 0.082           |          |
|  HEG1 |  KIAA0319L | 0.933 | 0.066           |          |
|  ITGA5 |  LNPEP | 0.933 | 0.168           |          |
|  NECTIN1 |  PTPRG | 0.932 | 0.088           |          |
|  CD276 |  PTPRK | 0.932 |            |          |
|  ITGA1 |  CD276 | 0.931 | 0.122           |          |
|  ITGA3 |  PTGFRN | 0.931 | 0.282           |          |
|  HEG1 |  LNPEP | 0.929 | 0.08           |          |
|  PTPRG |  KIAA0319L | 0.929 | 0.096           |          |
|  HEG1 |  ITGA2 | 0.927 | 0.086           |          |
|  ITGA1 |  ITGA2 | 0.923 | 0.196           |          |
|  CD276 |  PODXL | 0.92 | 0.028           |          |
|  MRC2 |  CSPG4 | 0.919 | 0.074           |          |
|  ITGA3 |  ITGA1 | 0.917 | 0.226           |
mutually_exclusive (P05556)        
|
|  PTPRG |  PTPRJ | 0.907 | 0.14           |          |
|  HEG1 |  ITGA5 | 0.906 | 0.11           |          |
|  NECTIN1 |  PTGFRN | 0.901 | 0.016           |          |
|  ITGA1 |  PTPRG | 0.899 | 0.156           |          |
|  MRC2 |  LNPEP | 0.897 | 0.06           |          |
|  ITGA2 |  KIAA0319L | 0.896 | 0.05           |          |
|  HEG1 |  PTPRG | 0.895 | 0.108           |          |
|  PTPRG |  ALCAM | 0.89 | 0.092           |          |
|  ENPP4 |  LGALS3 | 0.886 | 0.168           |
structurally_consistent (dimer)        
|
|  ITGA3 |  ALCAM | 0.885 | 0.17           |          |
|  ITGB1 |  LGALS3 | 0.884 | 0.262           |          |
|  ITGA5 |  PTPRJ | 0.883 | 0.148           |          |
|  ITGA2 |  PTPRK | 0.881 |            |          |
|  LNPEP |  PTPRK | 0.88 |            |          |
|  PTPRG |  ITGA5 | 0.88 | 0.088           |          |
|  ITGB1 |  PTGFRN | 0.878 | 0.14           |          |
|  ITGB1 |  ENPP4 | 0.872 | 0.358277777778           |          |
|  NECTIN1 |  PODXL | 0.871 | 0.05           |          |
|  NECTIN1 |  ALCAM | 0.871 | 0.06           |          |
|  PTPRG |  PTPRK | 0.869 |            |          |
|  KIAA0319L |  ITGA5 | 0.867 | 0.056           |          |
|  CD276 |  CSPG4 | 0.866 | 0.044           |          |
|  PTGFRN |  PTPRK | 0.86 |            |          |
|  ITGA1 |  CSPG4 | 0.859 | 0.192           |          |
|  ITGA1 |  PODXL | 0.858 | 0.052           |          |
|  KIAA0319L |  PTGFRN | 0.854 | 0.038           |          |
|  ENPP4 |  PTGFRN | 0.852 | 0.048           |          |
|  HEG1 |  PTGFRN | 0.851 | 0.062           |          |
|  ITGA5 |  CSPG4 | 0.848 | 0.118           |          |
|  NECTIN1 |  CD276 | 0.845 | 0.05           |          |
|  LGALS3 |  PTPRG | 0.842 | 0.168           |          |
|  LNPEP |  CSPG4 | 0.841 | 0.038           |          |
|  PTPRG |  CSPG4 | 0.839 | 0.102           |          |
|  NECTIN1 |  KIAA0319L | 0.838 | 0.036           |          |
|  NECTIN1 |  LNPEP | 0.837 | 0.042           |          |
|  NECTIN1 |  PTPRK | 0.834 |            |          |
|  ITGA1 |  SDK1 | 0.832 |            |          |
|  ITGA3 |  CD276 | 0.827 | 0.054           |          |
|  SDK1 |  CSPG4 | 0.826 |            |          |
|  HEG1 |  ITGA3 | 0.82 | 0.106           |          |
|  PODXL |  ITGA5 | 0.815 | 0.066           |          |
|  ITGA3 |  PTPRJ | 0.815 | 0.126           |          |
|  PODXL |  LNPEP | 0.809 | 0.032           |          |
|  CD276 |  ITGA5 | 0.809 | 0.062           |          |
|  ITGA2 |  MRC2 | 0.805 | 0.078           |          |
|  ITGA2 |  LNPEP | 0.798 | 0.088           |          |
|  ITGB1 |  NECTIN1 | 0.793 | 0.266513586957           |          |
|  ENPP4 |  ITGA1 | 0.791 | 0.078           |
mutually_exclusive (P17931)        
|
|  ITGB1 |  KIAA0319L | 0.79 | 0.128           |          |
|  ITGB1 |  CSPG4 | 0.787 | 0.202           |          |
|  ITGA3 |  PTPRG | 0.783 | 0.144           |          |
|  HEG1 |  CD276 | 0.783 | 0.032           |          |
|  LGALS3 |  LGALS8 | 0.779 | 0.032           |          |
|  ITGB1 |  MRC2 | 0.778 | 0.23           |          |
|  ENPP4 |  KIAA0319L | 0.767 | 0.09           |          |
|  ENPP4 |  CSPG4 | 0.766 | 0.088           |          |
|  ITGA3 |  MRC2 | 0.764 | 0.116           |          |
|  ITGB1 |  HEG1 | 0.763 | 0.257415053763           |          |
|  ITGA5 |  PTPRK | 0.761 |            |          |
|  PTPRJ |  KIAA1549 | 0.756 | 0.08           |          |
|  ITGB1 |  ALCAM | 0.753 | 0.212           |          |
|  NECTIN1 |  MRC2 | 0.742 | 0.0265           |          |
|  KIAA1549 |  PTPRK | 0.739 |            |          |
|  CSPG4 |  KIAA1549 | 0.732 | 0.076           |          |
|  PTPRG |  MRC2 | 0.724 | 0.054           |          |
|  ITGA3 |  LNPEP | 0.722 | 0.086           |          |
|  LGALS3 |  SDK1 | 0.708 |            |          |
|  CD276 |  ALCAM | 0.706 | 0.106           |          |
|  ITGA5 |  MRC2 | 0.704 | 0.146           |          |
|  ITGA2 |  PTPRG | 0.698 | 0.108           |          |
|  ALCAM |  KIAA1549 | 0.693 | 0.08           |          |
|  ITGA3 |  KIAA0319L | 0.69 | 0.038           |          |
|  KIAA0319L |  MRC2 | 0.688 | 0.062           |          |
|  PTPRG |  CD276 | 0.68 | 0.088           |          |
|  ITGA5 |  PTGFRN | 0.677 | 0.158           |          |
|  ITGA3 |  PODXL | 0.674 | 0.176           |          |
|  CD276 |  PTGFRN | 0.667 | 0.194           |          |
|  ITGA5 |  ALCAM | 0.666 | 0.198           |          |
|  ITGB1 |  CD276 | 0.651 | 0.112           |          |
|  PTPRG |  CSF3 | 0.634 |            |          |
|  SDK1 |  ALCAM | 0.632 |            |          |
|  ENPP4 |  CD276 | 0.632 | 0.048           |          |
|  PODXL |  SDK1 | 0.632 |            |          |
|  FLT4 |  ALCAM | 0.632 | 0.146           |          |
|  LGALS3 |  CD276 | 0.624 | 0.08           |          |
|  FLT4 |  PTPRK | 0.623 |            |          |
|  SDK1 |  KIAA1549 | 0.622 |            |          |
|  HEG1 |  KIAA1549 | 0.622 | 0.09           |          |
|  HEG1 |  SDK1 | 0.619 |            |          |
|  SDK1 |  PTPRJ | 0.619 |            |          |
|  ENPP4 |  LNPEP | 0.614 | 0.064           |          |
|  ITGA1 |  KIAA1549 | 0.61 | 0.084           |          |
|  SDK1 |  MRC2 | 0.602 |            |          |
|  ITGA8 |  LNPEP | 0.602 |            |          |
|  LGALS3 |  ITGA1 | 0.596 | 0.174           |
structurally_consistent (dimer)        
|
|  SDK1 |  PTPRK | 0.592 |            |          |
|  KIAA0319L |  SDK1 | 0.592 |            |          |
|  ITGA2 |  SDK1 | 0.583 |            |          |
|  PTPRG |  LNPEP | 0.571 | 0.08           |          |
|  SDK1 |  FLT4 | 0.566 |            |          |
|  PTPRG |  PTGFRN | 0.565 | 0.036           |          |
|  MRC2 |  KIAA1549 | 0.562 | 0.074           |          |
|  PODXL |  KIAA1549 | 0.561 | 0.04           |          |
|  CD276 |  MRC2 | 0.509 | 0.206           |          |
|  KIAA0319L |  FLT4 | 0.506 | 0.054           |          |
|  ITGA8 |  PTGFRN | 0.497 |            |          |
|  ITGA2 |  PODXL | 0.479 | 0.064           |          |
|  ITGA5 |  SDK1 | 0.478 |            |          |
|  ENPP4 |  PTPRK | 0.469 |            |          |
|  CD276 |  SDK1 | 0.467 |            |          |
|  ENPP4 |  SDK1 | 0.466 |            |          |
|  PODXL |  PTGFRN | 0.459 | 0.028           |          |
|  ITGA2 |  CD276 | 0.458 | 0.068           |          |
|  ITGA3 |  NECTIN1 | 0.457 | 0.062           |          |
|  NECTIN1 |  CSPG4 | 0.452 | 0.148           |          |
|  HEG1 |  FLT4 | 0.447 | 0.1           |          |
|  LGALS3 |  ITGA3 | 0.446 | 0.146           |          |
|  ENPP4 |  PTPRG | 0.444 | 0.048           |          |
|  FLT4 |  KIAA1549 | 0.424 | 0.098           |          |
|  ENPP4 |  HEG1 | 0.42 | 0.072           |          |
|  NECTIN1 |  ITGA2 | 0.412 | 0.112           |          |
|  LGALS3 |  ITGA5 | 0.405 | 0.056           |          |
|  ITGB1 |  PTPRG | 0.402 | 0.284           |          |
|  NECTIN1 |  SDK1 | 0.401 |            |          |
|  PODXL |  MRC2 | 0.396 | 0.054           |          |
|  SDK1 |  LNPEP | 0.388 |            |          |
|  KIAA0319L |  KIAA1549 | 0.384 | 0.07           |          |
|  SDK1 |  PTGFRN | 0.378 |            |          |
|  PTGFRN |  KIAA1549 | 0.368 | 0.034           |          |
|  CD276 |  KIAA1549 | 0.366 | 0.104           |          |
|  FLT4 |  PTPRJ | 0.366 | 0.082           |          |
|  ITGA1 |  FLT4 | 0.366 | 0.128583333333           |          |
|  FLT4 |  CSPG4 | 0.362 | 0.076           |          |
|  LNPEP |  KIAA1549 | 0.353 | 0.102           |          |
|  ENPP4 |  PODXL | 0.346 | 0.066           |          |
|  ENPP4 |  KIAA1549 | 0.346 | 0.07           |          |
|  ENPP4 |  ITGA3 | 0.344 | 0.072           |          |
|  PODXL |  FLT4 | 0.344 | 0.126           |          |
|  NECTIN1 |  KIAA1549 | 0.33 | 0.082           |          |
|  ITGA8 |  MRC2 | 0.308 |            |          |
|  ITGB1 |  SDK1 | 0.295 |            |          |
|  ENPP4 |  ITGA2 | 0.291 | 0.11           |          |
|  PTPRG |  KIAA1549 | 0.289 | 0.078           |          |
|  LGALS3 |  FLT4 | 0.28 | 0.11           |          |
|  FLT4 |  LNPEP | 0.27 | 0.228           |          |
|  ITGA3 |  SDK1 | 0.261 |            |          |
|  NECTIN1 |  FLT4 | 0.255 | 0.108           |          |
|  ITGA8 |  ITGA2 | 0.243 |            |          |
|  ITGA2 |  KIAA1549 | 0.228 | 0.08           |          |
|  ENPP4 |  FLT4 | 0.202 | 0.088           |          |
|  ITGA5 |  KIAA1549 | 0.202 | 0.098           |          |
|  PTPRG |  SDK1 | 0.198 |            |          |
|  ITGB1 |  KIAA1549 | 0.194 | 0.256630769231           |          |
|  FLT4 |  MRC2 | 0.187 | 0.114           |          |
|  ITGA2 |  FLT4 | 0.171 | 0.098           |          |
|  ENPP4 |  NECTIN1 | 0.17 | 0.04           |          |
|  ITGA3 |  FLT4 | 0.161 | 0.076           |          |
|  FLT4 |  PTGFRN | 0.153 | 0.044           |          |
|  ITGA5 |  FLT4 | 0.151 | 0.122           |          |
|  ENPP4 |  ITGA5 | 0.15 | 0.056           |          |
|  LGALS3 |  ITGA2 | 0.122 | 0.21           |          |
|  ITGA3 |  KIAA1549 | 0.121 | 0.078           |          |
|  KIAA0319L |  CSF3 | 0.114 |            |          |
|  ITGB1 |  PODXL | 0.11 | 0.114           |          |
|  ITGB1 |  FLT4 | 0.109 | 0.26975803787           |          |
|  LGALS3 |  NECTIN1 | 0.103 | 0.0663326923077           |          |
|  PTPRG |  FLT4 | 0.101 | 0.146           |          |
|  ITGA8 |  ITGA5 | 0.097 |            |
mutually_exclusive (P05556)        
|
|  CD276 |  FLT4 | 0.083 | 0.164           |          |
|  ITGA8 |  ALCAM | 0.082 |            |          |
|  ITGA8 |  PTPRJ | 0.081 |            |          |
|  ITGA8 |  ITGA1 | 0.079 |            |          |
|  ITGA8 |  ITGA3 | 0.078 |            |          |
|  ITGA8 |  HEG1 | 0.077 |            |          |
|  ITGA8 |  PTPRG | 0.07 |            |          |
|  ITGA8 |  SDK1 | 0.062 |            |          |
|  ITGA8 |  KIAA0319L | 0.056 |            |          |
|  LGALS3 |  PTPRK | 0.055 |            |          |
|  ITGA8 |  KIAA1549 | 0.051 |            |          |
|  ITGA8 |  CSPG4 | 0.051 |            |          |
|  ITGA8 |  CD276 | 0.05 |            |          |
|  ITGA8 |  ENPP4 | 0.046 |            |          |
|  ITGA8 |  NECTIN1 | 0.042 |            |          |
|  ITGA8 |  PODXL | 0.032 |            |          |
|  ITGA8 |  FLT4 | 0.027 |            |          |
|  ITGA8 |  LGALS8 | 0.021 |            |          |
|  ITGA8 |  LGALS3 | 0.008 |            |
structurally_consistent (P09382)        
|
Related Complexes