hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10512.1
Complex Portal: CPX-10935
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHAF1B | Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7) | 5 | UniProt NCBI |
| SUV39H2 | Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Lysine N-methyltransferase 1B) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2) | 5 | UniProt NCBI |
| CACNA1D | Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3) | 5 | UniProt NCBI |
| CBX5 | Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha) | 5 | UniProt NCBI |
| TCAP | Telethonin (Titin cap protein) | 5 | UniProt NCBI |
| CHAF1A | Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150) | 5 | UniProt NCBI |
| ATRX | Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1259 | 6.1565588648e-05 | 0.285714285714 | CHAF1B CHAF1A | Chromatin assembly complex (CAF-1 complex) |
| CORUM:2234 | 6.1565588648e-05 | 0.285714285714 | CHAF1B CHAF1A | Chromatin assembly complex (CAF-1 complex) |
| CORUM:2235 | 0.000205125012531 | 0.285714285714 | CHAF1B CHAF1A | ASF1-interacting protein complex |
| CORUM:1149 | 0.000573957048441 | 0.285714285714 | CHAF1B CHAF1A | Histone H3.1 complex |
| HP:0008221 | 0.0225866527703 | 0.285714285714 | CACNA1D ATRX | Adrenal hyperplasia |
| GO:0006325 | 0.0285361428578 | 0.714285714286 | ATRX SUV39H2 CHAF1B CHAF1A CBX5 | chromatin organization |
| GO:0033186 | 0.0294899169624 | 0.285714285714 | CHAF1B CHAF1A | CAF-1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CHAF1A | CHAF1B | 1.0 | 0.704 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () Malo bioplex3_HCT116 fraction | |
| SUV39H2 | CBX5 | 0.998 | 0.198 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CHAF1A | ATRX | 0.994 | 0.1 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () | |
| TCAP | CBX5 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CHAF1B | CBX5 | 0.993 | 0.05 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| CHAF1B | CACNA1D | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ATRX | CBX5 | 0.985 | 0.156 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| CHAF1A | CBX5 | 0.981 | 0.094 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () fraction | |
| CHAF1B | ATRX | 0.972 | 0.046 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| CHAF1A | CACNA1D | 0.455 | bioplex3_WMM WMM_only | ||
| CACNA1D | CBX5 | 0.22 | bioplex3_WMM WMM_only | ||
| CHAF1B | SUV39H2 | 0.102 | 0.034 | bioplex3_WMM WMM_only | |
| CHAF1A | SUV39H2 | 0.076 | 0.0762765957447 | bioplex3_WMM WMM_only |
Related Complexes