hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10519.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DEFA6 | Defensin-6 (Defensin, alpha 6) | 5 | UniProt NCBI |
| CCR2 | C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192) | 5 | UniProt NCBI |
| POTEE | POTE ankyrin domain family member E (ANKRD26-like family C member 1A) (Prostate, ovary, testis-expressed protein on chromosome 2) (POTE-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1461973 | 0.00157362645287 | 0.666666666667 | DEFA6 CCR2 | Defensins |
| REAC:R-HSA-6803157 | 0.0108549519561 | 0.666666666667 | DEFA6 CCR2 | Antimicrobial peptides |
| WP:WP4397 | 0.0165527833611 | 0.333333333333 | CCR2 | Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| DEFA6 | POTEE | 0.961 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CCR2 | POTEE | 0.957 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| DEFA6 | huMAP3_01391.1 huMAP3_10519.1 huMAP3_12386.1 huMAP3_13333.1 |
| CCR2 | huMAP3_03932.1 huMAP3_10519.1 huMAP3_12902.1 |
| POTEE | huMAP3_03932.1 huMAP3_10519.1 huMAP3_12902.1 |