hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10536.1
Complex Portal: CPX-11312
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CMTM4 | CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine-like factor superfamily member 4) | 5 | UniProt NCBI |
| LYPD3 | Ly6/PLAUR domain-containing protein 3 (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4) | 5 | UniProt NCBI |
| DNAJC22 | DnaJ homolog subfamily C member 22 | 2 | UniProt NCBI |
| TMEM245 | Transmembrane protein 245 (Protein CG-2) | 4 | UniProt NCBI |
| ULBP2 | UL16-binding protein 2 (ALCAN-alpha) (NKG2D ligand 2) (N2DL-2) (NKG2DL2) (Retinoic acid early transcript 1H) | 5 | UniProt NCBI |
| GPAA1 | Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1) | 5 | UniProt NCBI |
| RFT1 | Protein RFT1 homolog | 5 | UniProt NCBI |
| CIBAR1 | CBY1-interacting BAR domain-containing protein 1 | 5 | UniProt NCBI |
| TMC4 | Transmembrane channel-like protein 4 | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-163125 | 0.0016398008479 | 0.333333333333 | GPAA1 LYPD3 ULBP2 | Post-translational modification: synthesis of GPI-anchored proteins |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LYPD3 | DNAJC22 | 0.999 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| LYPD3 | TMEM245 | 0.998 | 0.108 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | |
| LYPD3 | GPAA1 | 0.993 | 0.084 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | |
| TMC4 | LYPD3 | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RFT1 | LYPD3 | 0.991 | 0.112 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | |
| RFT1 | TMEM245 | 0.986 | 0.176 | bioplex_WMM bioplex3_WMM WMM_only | |
| LYPD3 | CIBAR1 | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ULBP2 | LYPD3 | 0.975 | 0.104 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RFT1 | CMTM4 | 0.972 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only | |
| RFT1 | GPAA1 | 0.962 | 0.136 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| TMC4 | GPAA1 | 0.955 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TMC4 | DNAJC22 | 0.902 | bioplex3_WMM WMM_only | ||
| RFT1 | TMC4 | 0.824 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ULBP2 | DNAJC22 | 0.355 | bioplex3_WMM WMM_only | ||
| DNAJC22 | TMEM245 | 0.343 | bioplex3_WMM WMM_only | ||
| DNAJC22 | CIBAR1 | 0.343 | bioplex3_WMM WMM_only | ||
| TMC4 | ULBP2 | 0.243 | bioplex3_WMM WMM_only | ||
| TMC4 | TMEM245 | 0.22 | bioplex3_WMM WMM_only | ||
| TMC4 | CIBAR1 | 0.22 | bioplex3_WMM WMM_only | ||
| RFT1 | DNAJC22 | 0.157 | bioplex3_WMM WMM_only | ||
| DNAJC22 | GPAA1 | 0.156 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| GPAA1 | TMEM245 | 0.146 | 0.072 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| GPAA1 | CMTM4 | 0.139 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only | |
| CMTM4 | TMEM245 | 0.13 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only | |
| CIBAR1 | TMEM245 | 0.129 | 0.034 | bioplex3_WMM WMM_only | |
| ULBP2 | TMEM245 | 0.128 | 0.046 | bioplex3_WMM WMM_only | |
| ULBP2 | CIBAR1 | 0.063 | 0.118 | bioplex3_WMM WMM_only | |
| RFT1 | ULBP2 | 0.049 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only | |
| ULBP2 | GPAA1 | 0.028 | 0.052 | bioplex3_WMM WMM_only | |
| GPAA1 | CIBAR1 | 0.028 | 0.054 | bioplex3_WMM WMM_only | |
| RFT1 | CIBAR1 | 0.024 | 0.05 | bioplex3_WMM WMM_only |
Related Complexes