hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10547.1
Complex Portal: CPX-13134
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COA3 | Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (Coiled-coil domain-containing protein 56) (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa) | 5 | UniProt NCBI |
| TUBB1 | Tubulin beta-1 chain | 5 | UniProt NCBI |
| IL12RB1 | Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212) | 5 | UniProt NCBI |
| LYPLA2 | Acyl-protein thioesterase 2 (APT-2) (EC 3.1.2.-) (Lysophospholipase II) (LPL-II) (LysoPLA II) (Palmitoyl-protein hydrolase) (EC 3.1.2.22) | 5 | UniProt NCBI |
| TCP11L1 | T-complex protein 11-like protein 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2019 | 0.0498708842806 | 0.2 | IL12RB1 | IL12A-IL12B-IL12RB1 complex |
| CORUM:2020 | 0.0498708842806 | 0.2 | IL12RB1 | IL12B-IL12RB1-IL12RB2 complex |
| CORUM:2026 | 0.0498708842806 | 0.2 | IL12RB1 | IL12RB1-IL12RB2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IL12RB1 | LYPLA2 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| IL12RB1 | TUBB1 | 0.97 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TCP11L1 | IL12RB1 | 0.966 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| COA3 | TCP11L1 | 0.963 | 0.054 | hein_WMM bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| TCP11L1 | TUBB1 | 0.962 | 0.044 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TUBB1 | LYPLA2 | 0.129 | 0.2064 | bioplex3_WMM WMM_only | |
| TCP11L1 | LYPLA2 | 0.031 | 0.024 | bioplex3_WMM WMM_only | |
| COA3 | TUBB1 | 0.021 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only | |
| COA3 | LYPLA2 | 0.009 | 0.032 | bioplex_WMM WMM_only |
Related Complexes