hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10548.1
Complex Portal: CPX-18690
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KEAP1 | Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19) | 5 | UniProt NCBI |
| ZNG1A | Zinc-regulated GTPase metalloprotein activator 1A (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 1) (COBW domain-containing protein 1) (NPC-A-6 COBW domain-containing protein 1) (NPC-A-6) | 5 | UniProt NCBI |
| GH2 | Growth hormone variant (GH-V) (Growth hormone 2) (Placenta-specific growth hormone) | 5 | UniProt NCBI |
| ZNG1F | Zinc-regulated GTPase metalloprotein activator 1F (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 6) (COBW domain-containing protein 6) | 3 | UniProt NCBI |
| METAP1 | Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) | 5 | UniProt NCBI |
| ZNG1B | Zinc-regulated GTPase metalloprotein activator 1B (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 2) (COBW domain-containing protein 2) | 3 | UniProt NCBI |
| TCERG1 | Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| TF:M07093 | 0.00152694380207 | 0.428571428571 | ZNG1A ZNG1B ZNG1F | Factor: FoxH1; motif: NNSAATCCACA |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| METAP1 | GH2 | 0.997 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TCERG1 | ZNG1B | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| KEAP1 | ZNG1B | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| METAP1 | TCERG1 | 0.981 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only | |
| METAP1 | ZNG1A | 0.978 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TCERG1 | ZNG1A | 0.978 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ZNG1A | ZNG1B | 0.969 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNG1A | KEAP1 | 0.965 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ZNG1F | ZNG1A | 0.96 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| METAP1 | ZNG1B | 0.958 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ZNG1F | ZNG1B | 0.75 | bioplex_WMM bioplex3_WMM WMM_only | ||
| METAP1 | KEAP1 | 0.131 | 0.172 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| METAP1 | ZNG1F | 0.109 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNG1F | KEAP1 | 0.065 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| GH2 | ZNG1F | 0.028 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TCERG1 | ZNG1F | 0.027 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TCERG1 | KEAP1 | 0.003 | 0.268 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes