hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10550.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RBM15B | Putative RNA-binding protein 15B (One-twenty two protein 3) (HsOTT3) (HuOTT3) (RNA-binding motif protein 15B) | 5 | UniProt NCBI |
| METTL14 | N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) (hMETTL14) | 5 | UniProt NCBI |
| METTL3 | N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0036396 | 5.38272230028e-06 | 1.0 | METTL14 RBM15B METTL3 | RNA N6-methyladenosine methyltransferase complex |
| GO:0045293 | 2.74903317479e-05 | 1.0 | METTL14 RBM15B METTL3 | mRNA editing complex |
| GO:0021861 | 0.00421361424067 | 0.666666666667 | METTL14 METTL3 | forebrain radial glial cell differentiation |
| GO:0001510 | 0.00731242824493 | 1.0 | METTL14 RBM15B METTL3 | RNA methylation |
| GO:0001734 | 0.00842684400117 | 0.666666666667 | METTL14 METTL3 | mRNA (N6-adenosine)-methyltransferase activity |
| GO:0034708 | 0.0116771431902 | 1.0 | METTL14 RBM15B METTL3 | methyltransferase complex |
| GO:0060019 | 0.0140440992017 | 0.666666666667 | METTL14 METTL3 | radial glial cell differentiation |
| GO:0043414 | 0.0328130751425 | 1.0 | METTL14 RBM15B METTL3 | macromolecule methylation |
| GO:0032259 | 0.0368433884648 | 1.0 | METTL14 RBM15B METTL3 | methylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| METTL14 | METTL3 | 1.0 | 0.214 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM hein () Malo fraction |
| METTL3 | RBM15B | 0.981 | 0.088 | hein_WMM youn_WMM hein () |
| METTL14 | RBM15B | 0.192 | 0.128 | hein_WMM WMM_only |
Related Complexes