hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10552.1
Complex Portal: CPX-16729
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MST1R | Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] | 5 | UniProt NCBI |
| AXL | Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene) | 5 | UniProt NCBI |
| PCDHB16 | Protocadherin beta-16 (PCDH-beta-16) (Protocadherin-3X) | 5 | UniProt NCBI |
| PCDHB7 | Protocadherin beta-7 (PCDH-beta-7) | 4 | UniProt NCBI |
| C2CD2L | Phospholipid transfer protein C2CD2L (C2 domain-containing protein 2-like) (C2CD2-like) (Transmembrane protein 24) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2010 | 0.0498708842806 | 0.2 | AXL | AXL homodimer complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PCDHB16 | PCDHB7 | 0.998 |
mutually_exclusive (Q9Y5E6)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHB16 | C2CD2L | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| AXL | PCDHB7 | 0.986 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C2CD2L | PCDHB7 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MST1R | PCDHB7 | 0.961 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| AXL | C2CD2L | 0.615 | 0.102 | bioplex3_WMM WMM_only | |
| AXL | MST1R | 0.089 | 0.128 | bioplex3_WMM WMM_only | |
| AXL | PCDHB16 | 0.074 | bioplex3_WMM WMM_only | ||
| C2CD2L | MST1R | 0.067 | 0.112 | bioplex3_WMM WMM_only | |
| PCDHB16 | MST1R | 0.066 | bioplex3_WMM WMM_only |
Related Complexes