hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10561.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MARK2 | Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b) | 5 | UniProt NCBI |
| MARK1 | Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c) | 5 | UniProt NCBI |
| CERT1 | Ceramide transfer protein (hCERT) (Collagen type IV alpha-3-binding protein) (Goodpasture antigen-binding protein) (GPBP) (START domain-containing protein 11) (StARD11) (StAR-related lipid transfer protein 11) | 5 | UniProt NCBI |
| FUCA1 | Tissue alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucosidase I) (Alpha-L-fucoside fucohydrolase 1) (Alpha-L-fucosidase 1) | 5 | UniProt NCBI |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5090 | 0.000135925027505 | 0.6 | MARK2 MARK3 MARK1 | Complement system in neuronal development and plasticity |
| GO:0050321 | 0.00109385703544 | 0.6 | MARK2 MARK3 MARK1 | tau-protein kinase activity |
| WP:WP2038 | 0.00528162918062 | 0.4 | MARK2 MARK1 | Microtubule cytoskeleton regulation |
| GO:0048156 | 0.00875197805683 | 0.6 | MARK2 MARK3 MARK1 | tau protein binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MARK2 | FUCA1 | 0.993 | 0.014 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM |
| MARK2 | MARK3 | 0.984 | 0.14 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM WMM_only |
| CERT1 | FUCA1 | 0.972 | 0.002 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CERT1 | MARK3 | 0.966 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CERT1 | MARK1 | 0.965 | 0.076 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CERT1 | MARK2 | 0.931 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| MARK3 | FUCA1 | 0.775 | 0.026 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| MARK1 | MARK2 | 0.73 | 0.116 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
| MARK1 | MARK3 | 0.683 | 0.152 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
| MARK1 | FUCA1 | 0.24 | 0.066 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
Related Complexes