hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10579.1
Complex Portal: CPX-13493
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NCS1 | Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein) | 5 | UniProt NCBI |
| HPCAL1 | Hippocalcin-like protein 1 (Calcium-binding protein BDR-1) (HLP2) (Visinin-like protein 3) (VILIP-3) | 5 | UniProt NCBI |
| ABHD6 | Monoacylglycerol lipase ABHD6 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 6) | 5 | UniProt NCBI |
| MAP3K10 | Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) | 5 | UniProt NCBI |
| DTX2 | Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2) | 5 | UniProt NCBI |
| TIPARP | Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) (TCDD-inducible poly [ADP-ribose] polymerase) | 5 | UniProt NCBI |
| ANKRD33B | Ankyrin repeat domain-containing protein 33B | 2 | UniProt NCBI |
| SSX1 | Protein SSX1 (Cancer/testis antigen 5.1) (CT5.1) (Synovial sarcoma, X breakpoint 1) | 5 | UniProt NCBI |
| NCALD | Neurocalcin-delta | 5 | UniProt NCBI |
| MAP3K9 | Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1) | 5 | UniProt NCBI |
| HPCA | Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4877 | 0.0231182298902 | 0.181818181818 | MAP3K10 MAP3K9 | Host pathogen interaction of human coronaviruses MAPK signaling |
| HPA:0481352 | 0.0499008936436 | 0.272727272727 | NCALD HPCAL1 HPCA | small intestine; paneth cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NCALD | HPCA | 0.999 |
mutually_exclusive (A6NCL7)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAP3K10 | HPCA | 0.999 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAP3K9 | HPCA | 0.998 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NCALD | HPCAL1 | 0.998 | 0.088 |
mutually_exclusive (Q86UW9)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| HPCA | DTX2 | 0.997 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HPCAL1 | HPCA | 0.996 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ABHD6 | NCS1 | 0.995 | 0.04 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SSX1 | NCALD | 0.992 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAP3K9 | NCS1 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NCALD | ANKRD33B | 0.991 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HPCA | ANKRD33B | 0.991 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ABHD6 | HPCA | 0.989 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NCALD | DTX2 | 0.985 | 0.088 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only |
| TIPARP | DTX2 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MAP3K10 | DTX2 | 0.902 |
mutually_exclusive (P84074)
|
bioplex3_WMM WMM_only | |
| MAP3K9 | ANKRD33B | 0.902 |
mutually_exclusive (P84074)
|
bioplex3_WMM WMM_only | |
| NCALD | MAP3K10 | 0.902 | bioplex3_WMM WMM_only | ||
| MAP3K10 | ANKRD33B | 0.902 |
mutually_exclusive (P84074)
|
bioplex3_WMM WMM_only | |
| MAP3K9 | DTX2 | 0.902 | bioplex3_WMM WMM_only | ||
| HPCAL1 | MAP3K10 | 0.902 | bioplex3_WMM WMM_only | ||
| MAP3K10 | MAP3K9 | 0.902 |
mutually_exclusive (P84074)
|
bioplex3_WMM WMM_only | |
| ABHD6 | MAP3K10 | 0.869 | bioplex3_WMM WMM_only | ||
| HPCAL1 | DTX2 | 0.814 | 0.052 |
structurally_consistent (dimer)
|
bioplex3_WMM WMM_only |
| ABHD6 | DTX2 | 0.72 | 0.098 | bioplex3_WMM WMM_only | |
| HPCAL1 | MAP3K9 | 0.698 | bioplex3_WMM WMM_only | ||
| NCALD | MAP3K9 | 0.696 | bioplex3_WMM WMM_only | ||
| ABHD6 | ANKRD33B | 0.675 | bioplex3_WMM WMM_only | ||
| HPCAL1 | ANKRD33B | 0.646 | bioplex3_WMM WMM_only | ||
| ANKRD33B | DTX2 | 0.64 |
mutually_exclusive (P84074)
|
bioplex3_WMM WMM_only | |
| ABHD6 | MAP3K9 | 0.596 | bioplex3_WMM WMM_only | ||
| ABHD6 | HPCAL1 | 0.397 | 0.026 | bioplex3_WMM WMM_only | |
| ABHD6 | NCALD | 0.364 | 0.08 | bioplex3_WMM WMM_only | |
| HPCA | NCS1 | 0.027 | bioplex3_WMM WMM_only bioplex_WMM | ||
| HPCAL1 | NCS1 | 0.021 | 0.054 | bioplex3_WMM WMM_only bioplex_WMM | |
| NCALD | NCS1 | 0.019 | 0.088 |
mutually_exclusive (Q86UW9)
|
bioplex3_WMM WMM_only bioplex_WMM |
Related Complexes