hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10588.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DMWD | Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9) | 5 | UniProt NCBI |
| WDR48 | WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80) | 5 | UniProt NCBI |
| WDR20 | WD repeat-containing protein 20 (Protein DMR) | 5 | UniProt NCBI |
| USP46 | Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6635 | 7.01606139244e-10 | 0.75 | WDR48 USP46 WDR20 | WDR20-USP46-UAF1 complex |
| GO:0035800 | 3.84440695359e-06 | 0.75 | DMWD WDR20 WDR48 | deubiquitinase activator activity |
| CORUM:6637 | 5.12628525639e-06 | 0.5 | WDR48 USP46 | USP46-UAF1 complex |
| CORUM:6634 | 1.53774525569e-05 | 0.5 | WDR48 WDR20 | WDR20-USP12-UAF1 complex |
| GO:0016504 | 0.0025122894873 | 0.75 | DMWD WDR20 WDR48 | peptidase activator activity |
| CORUM:3176 | 0.049938562206 | 0.25 | WDR48 | USP1-UAF1 complex |
| CORUM:6636 | 0.049938562206 | 0.25 | WDR48 | USP12-UAF1 complex |
| CORUM:6638 | 0.049938562206 | 0.25 | WDR48 | USP1-UAF1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| WDR20 | WDR48 | 1.0 | 0.144 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 gupta_WMM boldt_WMM |
| WDR20 | USP46 | 1.0 | 0.232 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM |
| WDR48 | USP46 | 0.998 | 0.224 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM |
| WDR48 | DMWD | 0.983 | 0.092 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| USP46 | DMWD | 0.966 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| WDR20 | DMWD | 0.944 | 0.126 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes