hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10590.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| YTHDF3 | YTH domain-containing family protein 3 (DF3) | 5 | UniProt NCBI |
| YTHDF1 | YTH domain-containing family protein 1 (DF1) (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1) | 5 | UniProt NCBI |
| UBAP2L | Ubiquitin-associated protein 2-like (Protein NICE-4) (RNA polymerase II degradation factor UBAP2L) | 5 | UniProt NCBI |
| YTHDF2 | YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2) | 5 | UniProt NCBI |
| ZC3H7A | Zinc finger CCCH domain-containing protein 7A | 4 | UniProt NCBI |
| UBAP2 | Ubiquitin-associated protein 2 (UBAP-2) (RNA polymerase II degradation factor UBAP2) | 5 | UniProt NCBI |
| ZNF598 | E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0034063 | 5.88640060552e-06 | 0.666666666667 | YTHDF3 YTHDF2 YTHDF1 UBAP2L | stress granule assembly |
| GO:1990247 | 0.00042234232358 | 0.5 | YTHDF3 YTHDF1 YTHDF2 | N6-methyladenosine-containing RNA reader activity |
| GO:0000932 | 0.000476002909429 | 0.666666666667 | YTHDF3 UBAP2 YTHDF1 YTHDF2 | P-body |
| GO:0140517 | 0.00156505859778 | 0.5 | YTHDF3 YTHDF1 YTHDF2 | protein-RNA adaptor activity |
| GO:0045948 | 0.00387837112504 | 0.5 | YTHDF3 YTHDF1 YTHDF2 | positive regulation of translational initiation |
| GO:0036464 | 0.0286787058971 | 0.666666666667 | YTHDF3 UBAP2 YTHDF1 YTHDF2 | cytoplasmic ribonucleoprotein granule |
| GO:0003723 | 0.0382588428658 | 1.0 | UBAP2L YTHDF2 ZC3H7A YTHDF1 YTHDF3 UBAP2 | RNA binding |
| GO:0035770 | 0.0393385643362 | 0.666666666667 | YTHDF3 UBAP2 YTHDF1 YTHDF2 | ribonucleoprotein granule |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| YTHDF1 | YTHDF2 | 1.0 | 0.418 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| YTHDF3 | YTHDF1 | 0.999 | 0.596 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
| YTHDF3 | YTHDF2 | 0.997 | 0.612 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| UBAP2 | UBAP2L | 0.994 | 0.252 | youn () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| YTHDF3 | UBAP2L | 0.991 | 0.508 | hein_WMM youn () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
| YTHDF3 | ZNF598 | 0.974 | 0.15 | hein_WMM youn () bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| ZNF598 | UBAP2L | 0.965 | 0.438605990783 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| ZC3H7A | YTHDF3 | 0.957 | 0.188 | hein_WMM youn () bioplex3_WMM youn_WMM WMM_only |
| ZC3H7A | UBAP2L | 0.808 | 0.416 | hein_WMM youn () bioplex3_HEK293 bioplex3_WMM youn_WMM treiber_WMM WMM_only |
| ZC3H7A | UBAP2 | 0.588 | 0.122 | youn () bioplex3_WMM youn_WMM WMM_only |
| YTHDF1 | UBAP2 | 0.561 | 0.128 | youn () bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| ZC3H7A | ZNF598 | 0.487 | 0.052 | hein_WMM youn () youn_WMM WMM_only |
| ZNF598 | UBAP2 | 0.427 | 0.284 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| YTHDF2 | UBAP2L | 0.237 | 0.582 | youn () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| YTHDF1 | UBAP2L | 0.227 | 0.308 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| YTHDF3 | UBAP2 | 0.197 | 0.428 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM WMM_only |
| YTHDF2 | ZNF598 | 0.192 | 0.218 | hein_WMM youn () youn_WMM gupta_WMM fraction |
| YTHDF1 | ZNF598 | 0.059 | 0.172 | hein_WMM youn () bioplex3_WMM youn_WMM gupta_WMM fraction |
| YTHDF2 | UBAP2 | 0.041 | 0.22 | youn () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| ZC3H7A | YTHDF1 | 0.038 | 0.132 | youn () bioplex3_WMM youn_WMM WMM_only |
| ZC3H7A | YTHDF2 | 0.009 | 0.196 | youn () bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only |
Related Complexes