hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10592.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MACROH2A2 | Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2) | 5 | UniProt NCBI |
| MACROH2A1 | Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205) | 5 | UniProt NCBI |
| H2BW1 | Histone H2B type W-T (H2B histone family member W testis-specific) (H2B.W histone 1) | 5 | UniProt NCBI |
| PPM1G | Protein phosphatase 1G (EC 3.1.3.16) (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) | 5 | UniProt NCBI |
| H3-7 | Histone H3-7 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05322 | 0.000188471529119 | 0.6 | MACROH2A2 MACROH2A1 H2BW1 | Systemic lupus erythematosus |
| KEGG:04613 | 0.000496659427831 | 0.6 | MACROH2A2 MACROH2A1 H2BW1 | Neutrophil extracellular trap formation |
| KEGG:05034 | 0.000496659427831 | 0.6 | MACROH2A2 MACROH2A1 H2BW1 | Alcoholism |
| WP:WP4553 | 0.00290547066497 | 0.4 | MACROH2A2 MACROH2A1 | FBXL10 enhancement of MAP ERK signaling in diffuse large B cell lymphoma |
| GO:1901837 | 0.0140440992017 | 0.4 | MACROH2A2 MACROH2A1 | negative regulation of transcription of nucleolar large rRNA by RNA polymerase I |
| KEGG:03082 | 0.024008315736 | 0.4 | MACROH2A2 MACROH2A1 | ATP-dependent chromatin remodeling |
| GO:0001740 | 0.0280843539964 | 0.4 | MACROH2A2 MACROH2A1 | Barr body |
| KEGG:04217 | 0.0415700968186 | 0.4 | MACROH2A2 MACROH2A1 | Necroptosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MACROH2A2 | MACROH2A1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM | |
| PPM1G | MACROH2A2 | 0.997 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| H2BW1 | MACROH2A1 | 0.979 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| H2BW1 | PPM1G | 0.815 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| H2BW1 | MACROH2A2 | 0.761 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PPM1G | MACROH2A1 | 0.085 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes