hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10601.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| STXBP6 | Syntaxin-binding protein 6 (Amisyn) | 5 | UniProt NCBI |
| SNAP29 | Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29) | 5 | UniProt NCBI |
| PPFIBP2 | Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) | 5 | UniProt NCBI |
| STX1A | Syntaxin-1A (Neuron-specific antigen HPC-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:873 | 5.12628525639e-06 | 0.5 | SNAP29 STX1A | SNARE complex (STX1A, SNAP29) |
| KEGG:04130 | 0.00116323751441 | 0.5 | SNAP29 STX1A | SNARE interactions in vesicular transport |
| REAC:R-HSA-6794362 | 0.0246065982605 | 0.5 | PPFIBP2 STX1A | Protein-protein interactions at synapses |
| GO:0006906 | 0.0449670283878 | 0.75 | STXBP6 STX1A SNAP29 | vesicle fusion |
| GO:0090174 | 0.048062454325 | 0.75 | STXBP6 STX1A SNAP29 | organelle membrane fusion |
| CORUM:915 | 0.049938562206 | 0.25 | STX1A | SNARE complex (SNAP23, STX1A) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SNAP29 | STXBP6 | 0.998 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| STX1A | STXBP6 | 0.979 | 0.114 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PPFIBP2 | SNAP29 | 0.979 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SNAP29 | STX1A | 0.959 | 0.216 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| PPFIBP2 | STX1A | 0.675 | 0.178 | bioplex3_WMM WMM_only |
Related Complexes