hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10611.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
ZRANB2	Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing)	5	UniProt NCBI
PIP4K2A	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIP5KIII) (Phosphatidylinositol 5-Phosphate 4-Kinase) (PI5P4Kalpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(4)P-5-kinase B isoform) (PtdIns(4)P-5-kinase C isoform) (PtdIns(5)P-4-kinase isoform 2-alpha)	5	UniProt NCBI
PIP4K2B	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)	5	UniProt NCBI
GRM3	Metabotropic glutamate receptor 3 (mGluR3)	5	UniProt NCBI
PNISR	Arginine/serine-rich protein PNISR (PNN-interacting serine/arginine-rich protein) (SR-related protein) (SR-rich protein) (Serine/arginine-rich-splicing regulatory protein 130) (SRrp130) (Splicing factor, arginine/serine-rich 130) (Splicing factor, arginine/serine-rich 18)	5	UniProt NCBI
PIP4K2C	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)	5	UniProt NCBI
AHCYL1	S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2)	5	UniProt NCBI
NOLC1	Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)	5	UniProt NCBI
NOS1AP	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein)	5	UniProt NCBI
CHD9	Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein)	5	UniProt NCBI
PLCD3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-3) (Phospholipase C-delta-3) (PLC-delta-3)	5	UniProt NCBI
C1orf226	Uncharacterized protein C1orf226	2	UniProt NCBI
NFKBIL1	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8847453	6.00573149715e-07	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	Synthesis of PIPs in the nucleus
WP:WP5411	4.82873225869e-06	0.307692307692	PIP4K2A PLCD3 PIP4K2C PIP4K2B	Phosphatidyl inositol phosphate pathway
WP:WP4971	4.82873225869e-06	0.307692307692	PIP4K2A PLCD3 PIP4K2C PIP4K2B	Phosphoinositides metabolism
REAC:R-HSA-6811555	1.25797000422e-05	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	PI5P Regulates TP53 Acetylation
KEGG:00562	1.41416803014e-05	0.307692307692	PIP4K2A PLCD3 PIP4K2C PIP4K2B	Inositol phosphate metabolism
GO:0016309	2.74903317479e-05	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	1-phosphatidylinositol-5-phosphate 4-kinase activity
GO:1902633	2.74903317479e-05	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process
GO:1902635	2.74903317479e-05	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process
KEGG:04070	4.18767837774e-05	0.307692307692	PIP4K2A PLCD3 PIP4K2C PIP4K2B	Phosphatidylinositol signaling system
REAC:R-HSA-6804758	0.00060149652218	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	Regulation of TP53 Activity through Acetylation
GO:0016308	0.00153551162834	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	1-phosphatidylinositol-4-phosphate 5-kinase activity
REAC:R-HSA-1660499	0.00238139170508	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	Synthesis of PIPs at the plasma membrane
REAC:R-HSA-1483255	0.00864710862593	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	PI Metabolism
REAC:R-HSA-6811558	0.00938906912758	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
REAC:R-HSA-199418	0.0123132989826	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	Negative regulation of the PI3K/AKT network
REAC:R-HSA-9006925	0.0181459628874	0.307692307692	PIP4K2A PIP4K2C AHCYL1 PIP4K2B	Intracellular signaling by second messengers
GO:2000786	0.018559526455	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	positive regulation of autophagosome assembly
WP:WP51	0.0205618858844	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	Regulation of actin cytoskeleton
KEGG:04810	0.034675171035	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	Regulation of actin cytoskeleton
GO:0044090	0.0419240742765	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	positive regulation of vacuole organization
GO:0052742	0.0481879293545	0.230769230769	PIP4K2A PIP4K2C PIP4K2B	phosphatidylinositol kinase activity
CORUM:6371	0.0499717467432	0.0769230769231	GRM3	mGluR3-mGluR8 complex

Edges

Protein 1	Protein 2	Score	ProteomeHD
PIP4K2B	PIP4K2C	1.0	0.014
PIP4K2A	PIP4K2C	1.0	0.0883043478261
PIP4K2A	PIP4K2B	1.0	0.318
ZRANB2	NFKBIL1	0.999	0.064
ZRANB2	PIP4K2A	0.999	0.044
PIP4K2A	PLCD3	0.999	0.068
PIP4K2A	NOLC1	0.998
CHD9	NFKBIL1	0.997	0.24
PIP4K2A	NOS1AP	0.997	0.074
PIP4K2C	NOLC1	0.996
PLCD3	PIP4K2C	0.994	0.15
NFKBIL1	PIP4K2A	0.991	0.088
PIP4K2A	PNISR	0.99	0.024
ZRANB2	PIP4K2C	0.99	0.056
PIP4K2A	GRM3	0.983
PIP4K2C	NOS1AP	0.982	0.098
PIP4K2A	AHCYL1	0.974	0.048
NOS1AP	C1orf226	0.973	0.166
CHD9	PIP4K2A	0.972	0.088
PIP4K2B	NOS1AP	0.971	0.042
NFKBIL1	NOLC1	0.965
NFKBIL1	NOS1AP	0.96	0.13
PIP4K2A	C1orf226	0.952	0.104
AHCYL1	PLCD3	0.951	0.082
PIP4K2B	PLCD3	0.95	0.068
PLCD3	NOS1AP	0.948	0.18
NFKBIL1	AHCYL1	0.946	0.064
ZRANB2	PIP4K2B	0.907	0.064
PLCD3	PNISR	0.902	0.066
NFKBIL1	PIP4K2C	0.888	0.088
PLCD3	NOLC1	0.875
NFKBIL1	C1orf226	0.825	0.094
NFKBIL1	PLCD3	0.799	0.08
CHD9	PNISR	0.786	0.174
CHD9	PLCD3	0.754	0.134
ZRANB2	NOLC1	0.636
ZRANB2	CHD9	0.626	0.096
NFKBIL1	PIP4K2B	0.573	0.106
PIP4K2B	AHCYL1	0.552	0.042
CHD9	NOS1AP	0.541	0.136
PNISR	GRM3	0.502
AHCYL1	PIP4K2C	0.347	0.046
PIP4K2B	GRM3	0.333
GRM3	C1orf226	0.333
NOLC1	NOS1AP	0.32
ZRANB2	NOS1AP	0.306	0.058
CHD9	GRM3	0.303
ZRANB2	PNISR	0.27	0.104
CHD9	AHCYL1	0.262	0.158
PNISR	NOLC1	0.243
NFKBIL1	PNISR	0.234	0.104
ZRANB2	GRM3	0.213
PLCD3	C1orf226	0.211	0.072
CHD9	NOLC1	0.205
CHD9	C1orf226	0.198	0.106
NOLC1	GRM3	0.193
AHCYL1	NOS1AP	0.191	0.16
PNISR	C1orf226	0.189	0.108
PIP4K2C	C1orf226	0.188	0.072
AHCYL1	GRM3	0.18
PIP4K2B	NOLC1	0.178
PNISR	NOS1AP	0.167	0.114
CHD9	PIP4K2C	0.162	0.04
NFKBIL1	GRM3	0.15
PIP4K2C	GRM3	0.143
PLCD3	GRM3	0.142
PIP4K2B	C1orf226	0.131	0.078
ZRANB2	C1orf226	0.131	0.114
CHD9	PIP4K2B	0.127	0.096
GRM3	NOS1AP	0.123
NOLC1	C1orf226	0.106
ZRANB2	PLCD3	0.097	0.044
AHCYL1	PNISR	0.088	0.032
PIP4K2B	PNISR	0.082	0.022
PIP4K2C	PNISR	0.075	0.054
AHCYL1	C1orf226	0.06	0.092
ZRANB2	AHCYL1	0.056	0.06
AHCYL1	NOLC1	0.043

Related Complexes

Genename	Complexes
ZRANB2	huMAP3_00442.1 huMAP3_05601.1 huMAP3_05748.1 huMAP3_06097.1 huMAP3_07967.1 huMAP3_08141.1 huMAP3_09438.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10611.1 huMAP3_10753.1 huMAP3_11073.1
PIP4K2A	huMAP3_00550.1 huMAP3_00708.1 huMAP3_02291.1 huMAP3_02922.1 huMAP3_03481.1 huMAP3_05647.1 huMAP3_06847.1 huMAP3_07416.1 huMAP3_08199.1 huMAP3_08289.1 huMAP3_08432.1 huMAP3_08874.1 huMAP3_08914.1 huMAP3_09163.1 huMAP3_09657.1 huMAP3_09823.1 huMAP3_10366.1 huMAP3_10611.1 huMAP3_10883.1 huMAP3_10957.1 huMAP3_11931.1 huMAP3_12214.1 huMAP3_12350.1 huMAP3_13786.1 huMAP3_13857.1 huMAP3_14693.1
PIP4K2B	huMAP3_00550.1 huMAP3_00708.1 huMAP3_02291.1 huMAP3_03481.1 huMAP3_04301.1 huMAP3_06847.1 huMAP3_07416.1 huMAP3_07859.1 huMAP3_08199.1 huMAP3_08289.1 huMAP3_08432.1 huMAP3_08874.1 huMAP3_08914.1 huMAP3_09163.1 huMAP3_09657.1 huMAP3_09823.1 huMAP3_10366.1 huMAP3_10611.1 huMAP3_10753.1 huMAP3_10883.1 huMAP3_10957.1 huMAP3_11931.1 huMAP3_12214.1 huMAP3_12350.1 huMAP3_13786.1 huMAP3_13857.1
GRM3	huMAP3_02291.1 huMAP3_02922.1 huMAP3_03481.1 huMAP3_05647.1 huMAP3_06847.1 huMAP3_08199.1 huMAP3_08289.1 huMAP3_08432.1 huMAP3_08874.1 huMAP3_08914.1 huMAP3_09163.1 huMAP3_09657.1 huMAP3_09823.1 huMAP3_10611.1 huMAP3_10957.1 huMAP3_12214.1 huMAP3_12350.1 huMAP3_13786.1 huMAP3_13857.1 huMAP3_14693.1
PNISR	huMAP3_02291.1 huMAP3_02922.1 huMAP3_03481.1 huMAP3_05647.1 huMAP3_06847.1 huMAP3_08199.1 huMAP3_08289.1 huMAP3_08432.1 huMAP3_08874.1 huMAP3_08914.1 huMAP3_09163.1 huMAP3_09657.1 huMAP3_09823.1 huMAP3_10611.1 huMAP3_10957.1 huMAP3_11931.1 huMAP3_12028.1 huMAP3_12214.1 huMAP3_12350.1 huMAP3_13857.1 huMAP3_13971.1
PIP4K2C	huMAP3_01275.1 huMAP3_04301.1 huMAP3_05601.1 huMAP3_05855.1 huMAP3_07416.1 huMAP3_07859.1 huMAP3_08199.1 huMAP3_08289.1 huMAP3_08432.1 huMAP3_08874.1 huMAP3_08914.1 huMAP3_09163.1 huMAP3_09657.1 huMAP3_09823.1 huMAP3_10366.1 huMAP3_10611.1 huMAP3_10753.1 huMAP3_10883.1 huMAP3_10957.1 huMAP3_11931.1 huMAP3_12214.1 huMAP3_12350.1 huMAP3_13786.1 huMAP3_13857.1
AHCYL1	huMAP3_00550.1 huMAP3_02291.1 huMAP3_03410.1 huMAP3_03481.1 huMAP3_06847.1 huMAP3_07110.1 huMAP3_08199.1 huMAP3_08289.1 huMAP3_08432.1 huMAP3_08739.1 huMAP3_08874.1 huMAP3_09163.1 huMAP3_09280.1 huMAP3_09657.1 huMAP3_09823.1 huMAP3_10366.1 huMAP3_10611.1 huMAP3_10844.1 huMAP3_10957.1 huMAP3_13428.1 huMAP3_13742.1 huMAP3_14337.1
NOLC1	huMAP3_02291.1 huMAP3_08914.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10611.1 huMAP3_11931.1 huMAP3_13072.1 huMAP3_15090.1
NOS1AP	huMAP3_03481.1 huMAP3_04394.1 huMAP3_06573.1 huMAP3_06847.1 huMAP3_06938.1 huMAP3_07124.1 huMAP3_08199.1 huMAP3_08432.1 huMAP3_08493.1 huMAP3_08874.1 huMAP3_08914.1 huMAP3_09163.1 huMAP3_09303.1 huMAP3_09607.1 huMAP3_09823.1 huMAP3_10250.1 huMAP3_10469.1 huMAP3_10611.1 huMAP3_10753.1 huMAP3_10883.1 huMAP3_10957.1 huMAP3_11931.1 huMAP3_12350.1 huMAP3_13786.1
CHD9	huMAP3_00526.1 huMAP3_00550.1 huMAP3_04960.1 huMAP3_08289.1 huMAP3_08914.1 huMAP3_09657.1 huMAP3_10366.1 huMAP3_10611.1 huMAP3_11590.1 huMAP3_12211.1 huMAP3_13428.1 huMAP3_13786.1
PLCD3	huMAP3_00550.1 huMAP3_02291.1 huMAP3_03481.1 huMAP3_04301.1 huMAP3_06847.1 huMAP3_08199.1 huMAP3_08289.1 huMAP3_08432.1 huMAP3_08739.1 huMAP3_08874.1 huMAP3_09163.1 huMAP3_09657.1 huMAP3_09823.1 huMAP3_10366.1 huMAP3_10611.1 huMAP3_10753.1 huMAP3_10957.1 huMAP3_11931.1 huMAP3_12214.1 huMAP3_12350.1
C1orf226	huMAP3_03481.1 huMAP3_04394.1 huMAP3_06573.1 huMAP3_06847.1 huMAP3_07124.1 huMAP3_08432.1 huMAP3_08715.1 huMAP3_08914.1 huMAP3_09163.1 huMAP3_09303.1 huMAP3_09520.1 huMAP3_09607.1 huMAP3_10250.1 huMAP3_10469.1 huMAP3_10611.1 huMAP3_10883.1 huMAP3_10957.1 huMAP3_11931.1 huMAP3_12350.1 huMAP3_13786.1
NFKBIL1	huMAP3_00526.1 huMAP3_03529.1 huMAP3_06487.1 huMAP3_07248.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09438.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10611.1 huMAP3_11073.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10611.1