hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10624.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PKD2 | Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2) | 5 | UniProt NCBI |
| ARMC10 | Armadillo repeat-containing protein 10 (Splicing variant involved in hepatocarcinogenesis protein) | 5 | UniProt NCBI |
| LHFPL5 | LHFPL tetraspan subfamily member 5 protein (Lipoma HMGIC fusion partner-like 5 protein) (Tetraspan membrane protein of hair cell stereocilia) | 5 | UniProt NCBI |
| PKD2L2 | Polycystin-2-like protein 2 (Polycystin-2L2) (Polycystic kidney disease 2-like 2 protein) (Polycystin-L2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0050982 | 0.000510886175237 | 0.75 | PKD2 PKD2L2 LHFPL5 | detection of mechanical stimulus |
| GO:0009581 | 0.0106287970558 | 0.75 | PKD2 PKD2L2 LHFPL5 | detection of external stimulus |
| GO:0009582 | 0.0118300289699 | 0.75 | PKD2 PKD2L2 LHFPL5 | detection of abiotic stimulus |
| GO:0009612 | 0.0248327141789 | 0.75 | PKD2 PKD2L2 LHFPL5 | response to mechanical stimulus |
| CORUM:1071 | 0.0249718442456 | 0.25 | PKD2 | PKD2-FPC complex |
| CORUM:1927 | 0.049938562206 | 0.25 | PKD2 | PKD2-PACS1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ARMC10 | LHFPL5 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PKD2 | PKD2L2 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PKD2 | LHFPL5 | 0.951 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PKD2 | ARMC10 | 0.366 | 0.022 | bioplex3_WMM WMM_only |
Related Complexes