hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10638.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TMEM9 | Proton-transporting V-type ATPase complex assembly regulator TMEM9 (v-ATPase assembly regulator TMEM9) (Dermal papilla-derived protein 4) (Transmembrane protein 9) (Protein TMEM9) | 5 | UniProt NCBI |
| CLCN4 | H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4) | 5 | UniProt NCBI |
| ICOSLG | ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275) | 5 | UniProt NCBI |
| CD200 | OX-2 membrane glycoprotein (CD antigen CD200) | 5 | UniProt NCBI |
| CLCN5 | H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5) | 5 | UniProt NCBI |
| CLCN3 | H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005247 | 6.72425931667e-05 | 0.5 | CLCN5 CLCN4 CLCN3 | voltage-gated chloride channel activity |
| REAC:R-HSA-2672351 | 0.000305777502474 | 0.5 | CLCN5 CLCN4 CLCN3 | Stimuli-sensing channels |
| GO:0008308 | 0.00042234232358 | 0.5 | CLCN5 CLCN4 CLCN3 | voltage-gated monoatomic anion channel activity |
| KEGG:04613 | 0.00105119898913 | 0.5 | CLCN5 CLCN4 CLCN3 | Neutrophil extracellular trap formation |
| REAC:R-HSA-983712 | 0.0021512772376 | 0.5 | CLCN5 CLCN4 CLCN3 | Ion channel transport |
| GO:0005254 | 0.0271028431288 | 0.5 | CLCN5 CLCN4 CLCN3 | chloride channel activity |
| GO:0006821 | 0.0473097913612 | 0.5 | CLCN5 CLCN4 CLCN3 | chloride transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CLCN5 | CD200 | 0.996 | 0.046 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| CLCN5 | TMEM9 | 0.991 | 0.054 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| CLCN3 | TMEM9 | 0.982 | 0.12 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| CLCN4 | TMEM9 | 0.981 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CLCN3 | ICOSLG | 0.978 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CLCN5 | CLCN3 | 0.972 | 0.308 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| CLCN4 | CLCN3 | 0.634 | bioplex3_WMM WMM_only | |
| CLCN4 | CLCN5 | 0.633 | bioplex3_WMM WMM_only |
Related Complexes