hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10641.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
INTS11	Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68)	5	UniProt NCBI
INTS6	Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1)	5	UniProt NCBI
INTS3	Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A)	5	UniProt NCBI
INTS7	Integrator complex subunit 7 (Int7)	5	UniProt NCBI
INTS12	Integrator complex subunit 12 (Int12) (PHD finger protein 22)	5	UniProt NCBI
INTS9	Integrator complex subunit 9 (Int9) (Protein related to CPSF subunits of 74 kDa) (RC-74)	5	UniProt NCBI
INTS4	Integrator complex subunit 4 (Int4)	5	UniProt NCBI
INTS2	Integrator complex subunit 2 (Int2)	5	UniProt NCBI
FOXC1	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)	5	UniProt NCBI
INTS1	Integrator complex subunit 1 (Int1)	5	UniProt NCBI
INTS5	Integrator complex subunit 5 (Int5)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1153	3.94611657409e-31	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	Integrator complex
CORUM:1155	1.70987739726e-30	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	Integrator-RNAPII complex
GO:0032039	4.15719324504e-25	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	integrator complex
GO:0016180	2.38934400194e-23	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	snRNA processing
REAC:R-HSA-6807505	1.24616317405e-20	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	RNA polymerase II transcribes snRNA genes
GO:0016073	7.10469277373e-20	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	snRNA metabolic process
CORUM:1154	6.14266278829e-19	0.636363636364	INTS4 INTS6 INTS7 INTS5 INTS2 INTS11 INTS9	DSS1 complex
GO:0034243	5.6418638186e-18	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	regulation of transcription elongation by RNA polymerase II
GO:0032784	4.52589655741e-17	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	regulation of DNA-templated transcription elongation
GO:0006368	6.9760527975e-17	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	transcription elongation by RNA polymerase II
GO:0006354	3.64874795153e-16	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	DNA-templated transcription elongation
GO:0034472	6.77632780639e-14	0.636363636364	INTS6 INTS7 INTS5 INTS12 INTS2 INTS1 INTS9	snRNA 3'-end processing
GO:0034470	3.02884992251e-11	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	ncRNA processing
GO:0034660	1.41658313898e-09	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	ncRNA metabolic process
GO:0031123	2.59988219045e-09	0.636363636364	INTS6 INTS7 INTS5 INTS12 INTS2 INTS1 INTS9	RNA 3'-end processing
REAC:R-HSA-73857	2.20543046166e-08	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	RNA Polymerase II Transcription
REAC:R-HSA-74160	7.69459173595e-08	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	Gene expression (Transcription)
GO:0006396	7.85449100503e-08	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	RNA processing
GO:0140513	3.03987191608e-06	0.909090909091	INTS4 INTS6 INTS7 INTS5 INTS12 INTS9 INTS1 INTS3 INTS11 INTS2	nuclear protein-containing complex
GO:0006366	5.21186456064e-06	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	transcription by RNA polymerase II
GO:0006355	7.53691247935e-05	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of DNA-templated transcription
GO:2001141	8.05603852332e-05	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of RNA biosynthetic process
GO:0006351	0.000127015524712	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	DNA-templated transcription
GO:0032774	0.000142880142753	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	RNA biosynthetic process
GO:0051252	0.000258182136371	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of RNA metabolic process
GO:0034654	0.000568973562955	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	nucleobase-containing compound biosynthetic process
GO:0018130	0.000695422418697	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	heterocycle biosynthetic process
GO:0019438	0.00070360086061	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	aromatic compound biosynthetic process
GO:0019219	0.000706346376562	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of nucleobase-containing compound metabolic process
GO:1901362	0.000967632092806	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	organic cyclic compound biosynthetic process
WP:WP5345	0.00161560350135	0.272727272727	INTS4 INTS11 INTS9	1p36 copy number variation syndrome
GO:0016070	0.00308349463476	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	RNA metabolic process
GO:0010468	0.00469739513727	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of gene expression
GO:0044271	0.0050969753096	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	cellular nitrogen compound biosynthetic process
GO:0010556	0.00661322725549	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of macromolecule biosynthetic process
GO:0031326	0.00842368314941	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of cellular biosynthetic process
GO:0009889	0.00899012714611	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of biosynthetic process
GO:0005654	0.0105448660706	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	nucleoplasm
GO:0090304	0.0119029444692	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	nucleic acid metabolic process
GO:0051171	0.0210338225181	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of nitrogen compound metabolic process
GO:0031981	0.0214587900711	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	nuclear lumen
GO:0080090	0.0275866537037	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	regulation of primary metabolic process
GO:0006139	0.0379532315546	1.0	INTS4 INTS6 INTS7 INTS5 INTS12 INTS1 INTS9 FOXC1 INTS3 INTS11 INTS2	nucleobase-containing compound metabolic process

Edges

Protein 1	Protein 2	Score	ProteomeHD
INTS9	INTS11	1.0	0.91
INTS9	INTS4	1.0	0.414
INTS1	INTS12	1.0	0.49
INTS12	INTS4	1.0	0.614
INTS5	INTS4	0.998	0.906
INTS11	INTS4	0.998	0.494
INTS5	INTS12	0.997	0.478
INTS3	INTS1	0.996	0.732
INTS1	INTS2	0.996	0.418
INTS5	INTS2	0.996	0.774
INTS7	INTS5	0.996	0.912
INTS4	INTS2	0.994	0.492
INTS5	INTS9	0.994	0.558
INTS6	INTS4	0.993	0.886
INTS7	INTS4	0.992	0.764
INTS6	INTS11	0.99	0.56
INTS6	INTS9	0.986	0.48
INTS7	INTS2	0.985	0.79
FOXC1	INTS1	0.985	0.088
INTS3	INTS11	0.982	0.298
INTS1	INTS4	0.981	0.774
INTS3	INTS12	0.98	0.392
INTS12	INTS2	0.971	0.258
INTS6	INTS3	0.971	0.308
INTS5	INTS6	0.968	0.874
INTS3	INTS4	0.967	0.612
FOXC1	INTS6	0.965	0.1
FOXC1	INTS12	0.962	0.148
INTS5	INTS11	0.961	0.734
INTS7	INTS11	0.958	0.208
INTS3	INTS2	0.955	0.296
INTS6	INTS1	0.955	0.728
INTS6	INTS12	0.954	0.48
INTS6	INTS2	0.954	0.414
INTS7	INTS1	0.949	0.456
INTS7	INTS12	0.944	0.326
INTS12	INTS9	0.936	0.564
INTS5	INTS1	0.932	0.694
INTS11	INTS2	0.891	0.124
INTS5	INTS3	0.881	0.564
INTS12	INTS11	0.86	0.432
INTS9	INTS2	0.809	0.272
INTS7	INTS3	0.785	0.556
FOXC1	INTS3	0.775	0.072
FOXC1	INTS9	0.763	0.04
FOXC1	INTS4	0.737	0.086
INTS1	INTS11	0.709	0.476
INTS1	INTS9	0.688	0.394
FOXC1	INTS2	0.655	0.08
FOXC1	INTS5	0.552	0.054
INTS3	INTS9	0.311	0.268
INTS7	INTS9	0.302	0.502
FOXC1	INTS11	0.282	0.046
FOXC1	INTS7	0.142	0.062
INTS7	INTS6	0.066	0.45

Related Complexes

Genename	Complexes
INTS11	huMAP3_06382.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_15286.1
INTS6	huMAP3_01810.1 huMAP3_04137.1 huMAP3_04823.1 huMAP3_06989.1 huMAP3_08147.1 huMAP3_08278.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_10684.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
INTS3	huMAP3_01810.1 huMAP3_02054.1 huMAP3_07468.1 huMAP3_07627.1 huMAP3_07821.1 huMAP3_08147.1 huMAP3_08870.1 huMAP3_09230.1 huMAP3_09666.1 huMAP3_10202.1 huMAP3_10287.1 huMAP3_10641.1 huMAP3_10684.1 huMAP3_11232.1 huMAP3_13648.1 huMAP3_14291.1
INTS7	huMAP3_01623.1 huMAP3_05510.1 huMAP3_06989.1 huMAP3_10641.1 huMAP3_11025.1
INTS12	huMAP3_04823.1 huMAP3_06382.1 huMAP3_06914.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10153.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_15286.1
INTS9	huMAP3_05510.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
INTS4	huMAP3_06382.1 huMAP3_06914.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
INTS2	huMAP3_06382.1 huMAP3_09230.1 huMAP3_10641.1 huMAP3_11232.1 huMAP3_12564.1
FOXC1	huMAP3_00847.1 huMAP3_04823.1 huMAP3_06695.1 huMAP3_06989.1 huMAP3_07998.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_10641.1 huMAP3_13510.1
INTS1	huMAP3_04823.1 huMAP3_06382.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1
INTS5	huMAP3_01623.1 huMAP3_05510.1 huMAP3_06989.1 huMAP3_08985.1 huMAP3_09363.1 huMAP3_10641.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10641.1