hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10663.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TOP3B | DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1) | 5 | UniProt NCBI |
| FXR1 | RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p) | 5 | UniProt NCBI |
| TDRD3 | Tudor domain-containing protein 3 | 5 | UniProt NCBI |
| FMR1 | Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7407 | 5.12628525639e-06 | 0.5 | TOP3B TDRD3 | TOP3B-c complex |
| GO:0140225 | 0.0028092043205 | 0.5 | TOP3B TDRD3 | DNA topoisomerase III-beta-TDRD3 complex |
| GO:0033592 | 0.00842684400117 | 0.5 | FMR1 FXR1 | RNA strand annealing activity |
| GO:0044326 | 0.00842684400117 | 0.5 | FMR1 FXR1 | dendritic spine neck |
| GO:1902737 | 0.0168521501606 | 0.5 | FMR1 FXR1 | dendritic filopodium |
| CORUM:5360 | 0.049938562206 | 0.25 | FXR1 | AGO2-FXR1-TNF(alpha)ARE-RNP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TOP3B | TDRD3 | 0.999 | 0.425307692308 | hein_WMM youn () bioplex3_HEK293 Guru bioplex3_WMM youn_WMM gupta_WMM fraction |
| FXR1 | FMR1 | 0.998 | 0.446 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM treiber_WMM |
| TOP3B | FMR1 | 0.986 | 0.336 | hein_WMM youn () bioplex3_WMM youn_WMM treiber_WMM WMM_only |
| TOP3B | FXR1 | 0.985 | 0.2225 | hein_WMM youn () bioplex3_HEK293 bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| TDRD3 | FMR1 | 0.738 | 0.114 | hein_WMM youn () bioplex3_WMM youn_WMM gupta_WMM fraction |
| TDRD3 | FXR1 | 0.552 | 0.092 | hein_WMM youn () bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes