List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_10668.1

Confidence: Medium High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
FANCB	Fanconi anemia group B protein (Protein FACB) (Fanconi anemia-associated polypeptide of 95 kDa) (FAAP95)	5	UniProt   NCBI
FANCL	E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL)	5	UniProt   NCBI
CDH16	Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin)	5	UniProt   NCBI
FANCC	Fanconi anemia group C protein (Protein FACC)	5	UniProt   NCBI
GRK7	Rhodopsin kinase GRK7 (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7)	5	UniProt   NCBI
IL6R	Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126) [Cleaved into: Soluble interleukin-6 receptor subunit alpha (sIL6R)]	5	UniProt   NCBI
FAAP100	Fanconi anemia core complex-associated protein 100 (Fanconi anemia-associated protein of 100 kDa)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1624	1.34496026232e-10	0.571428571429	FAAP100 FANCB FANCC FANCL	FA core complex (Fanconi anemia core complex)
CORUM:245	1.34496026232e-10	0.571428571429	FAAP100 FANCB FANCC FANCL	FA core complex (Fanconi anemia core complex)
CORUM:6884	2.4205307311e-10	0.571428571429	FAAP100 FANCB FANCC FANCL	Fanconi anemia FAAP100 complex
CORUM:6885	7.02338504734e-09	0.428571428571	FAAP100 FANCB FANCL	L-B-P100 subcomplex
REAC:R-HSA-6783310	1.85951185977e-07	0.571428571429	FAAP100 FANCB FANCC FANCL	Fanconi Anemia Pathway
KEGG:03460	2.0217832396e-07	0.571428571429	FAAP100 FANCB FANCC FANCL	Fanconi anemia pathway
CORUM:1152	2.45616649736e-07	0.428571428571	FANCB FANCC FANCL	FA complex (Fanconi anemia complex)
GO:0043240	4.5526752727e-07	0.571428571429	FAAP100 FANCB FANCC FANCL	Fanconi anaemia nuclear complex
CORUM:2739	8.41595542506e-07	0.428571428571	FANCB FANCC FANCL	FA complex (Fanconi anemia complex)
WP:WP4946	1.05510723277e-05	0.571428571429	FAAP100 FANCB FANCC FANCL	DNA repair pathways full network
GO:0036297	3.75057231239e-05	0.571428571429	FAAP100 FANCB FANCC FANCL	interstrand cross-link repair
HP:0005522	8.74693219996e-05	0.428571428571	FANCB FANCC FANCL	Pyridoxine-responsive sideroblastic anemia
HP:0010469	0.000100569052035	0.428571428571	FANCB FANCC FANCL	Absent testis
HP:0003974	0.000114912442479	0.428571428571	FANCB FANCC FANCL	Absent radius
HP:0009822	0.000130555487924	0.428571428571	FANCB FANCC FANCL	Aplasia involving forearm bones
HP:0003953	0.000130555487924	0.428571428571	FANCB FANCC FANCL	Absent forearm bone
GO:0006513	0.000136293772339	0.571428571429	FAAP100 FANCB FANCC FANCL	protein monoubiquitination
HP:0012848	0.000165964290174	0.428571428571	FANCB FANCC FANCL	Small intestinal stenosis
HP:0010293	0.000165964290174	0.428571428571	FANCB FANCC FANCL	Aplasia/Hypoplasia of the uvula
HP:0100867	0.000165964290174	0.428571428571	FANCB FANCC FANCL	Duodenal stenosis
HP:0100760	0.000185841804214	0.428571428571	FANCB FANCC FANCL	Clubbing of toes
HP:0002245	0.000185841804214	0.428571428571	FANCB FANCC FANCL	Meckel diverticulum
HP:0100587	0.000230222103566	0.428571428571	FANCB FANCC FANCL	Abnormal preputium morphology
HP:0001924	0.000281140951458	0.428571428571	FANCB FANCC FANCL	Sideroblastic anemia
CORUM:1625	0.000307617328197	0.285714285714	FANCB FANCC	FA core complex (Fanconi anemia core complex)
HP:0001549	0.000439963868771	0.428571428571	FANCB FANCC FANCL	Abnormal ileum morphology
CORUM:248	0.000737776422886	0.285714285714	FANCL FANCC	BRAFT complex
HP:0000813	0.000802165341459	0.428571428571	FANCB FANCC FANCL	Bicornuate uterus
HP:0007874	0.000977145370486	0.428571428571	FANCB FANCC FANCL	Almond-shaped palpebral fissure
HP:0100026	0.00104065814502	0.428571428571	FANCB FANCC FANCL	Arteriovenous malformation
CORUM:244	0.00112664416828	0.285714285714	FANCL FANCC	BRAFT complex
HP:0003022	0.00117579195141	0.428571428571	FANCB FANCC FANCL	Hypoplasia of the ulna
REAC:R-HSA-73894	0.00121626736244	0.571428571429	FAAP100 FANCB FANCC FANCL	DNA Repair
HP:0003220	0.00124752252588	0.428571428571	FANCB FANCC FANCL	Abnormality of chromosome stability
HP:0009777	0.00132210183309	0.428571428571	FANCB FANCC FANCL	Absent thumb
HP:0200005	0.00132210183309	0.428571428571	FANCB FANCC FANCL	Abnormal shape of the palpebral fissure
HP:0006495	0.00148002522626	0.428571428571	FANCB FANCC FANCL	Aplasia/Hypoplasia of the ulna
HP:0007565	0.00164999883348	0.428571428571	FANCB FANCC FANCL	Multiple cafe-au-lait spots
HP:0001199	0.00234608959709	0.428571428571	FANCB FANCC FANCL	Triphalangeal thumb
HP:0000072	0.00257567372155	0.428571428571	FANCB FANCC FANCL	Hydroureter
HP:0009821	0.00307859089363	0.428571428571	FANCB FANCC FANCL	Forearm undergrowth
HP:0006501	0.00321374930888	0.428571428571	FANCB FANCC FANCL	Aplasia/Hypoplasia of the radius
HP:0008572	0.00379371448362	0.428571428571	FANCB FANCC FANCL	External ear malformation
HP:0009380	0.00394880725781	0.428571428571	FANCB FANCC FANCL	Aplasia of the fingers
HP:0009824	0.00443918702397	0.428571428571	FANCB FANCC FANCL	Upper limb undergrowth
HP:0002246	0.00443918702397	0.428571428571	FANCB FANCC FANCL	Abnormal duodenum morphology
HP:0005344	0.00478755978401	0.428571428571	FANCB FANCC FANCL	Abnormal carotid artery morphology
HP:0002575	0.0055377143869	0.428571428571	FANCB FANCC FANCL	Tracheoesophageal fistula
HP:0000027	0.00594034849588	0.428571428571	FANCB FANCC FANCL	Azoospermia
HP:0006503	0.00614874082901	0.428571428571	FANCB FANCC FANCL	Aplasia/hypoplasia involving forearm bones
HP:0012745	0.00931276773117	0.428571428571	FANCB FANCC FANCL	Short palpebral fissure
HP:0008669	0.0107696849607	0.428571428571	FANCB FANCC FANCL	Abnormal spermatogenesis
HP:0002863	0.0107696849607	0.428571428571	FANCB FANCC FANCL	Myelodysplasia
HP:0010161	0.0110780643926	0.428571428571	FANCB FANCC FANCL	Abnormal toe phalanx morphology
HP:0001053	0.0110780643926	0.428571428571	FANCB FANCC FANCL	Hypopigmented skin patches
HP:0000957	0.0127078129037	0.428571428571	FANCB FANCC FANCL	Cafe-au-lait spot
HP:0009892	0.0129659395038	0.285714285714	FANCB FANCL	Anotia
HP:0000453	0.0130516973888	0.428571428571	FANCB FANCC FANCL	Choanal atresia
HP:0008053	0.0130516973888	0.428571428571	FANCB FANCC FANCL	Aplasia/Hypoplasia of the iris
HP:0008055	0.0130516973888	0.428571428571	FANCB FANCC FANCL	Aplasia/Hypoplasia affecting the uvea
HP:0002414	0.0134016814301	0.428571428571	FANCB FANCC FANCL	Spina bifida
HP:0001217	0.0137578169218	0.428571428571	FANCB FANCC FANCL	Clubbing
HP:0000415	0.0160267107767	0.428571428571	FANCB FANCC FANCL	Abnormality of the choanae
HP:0008062	0.0164273557067	0.428571428571	FANCB FANCC FANCL	Aplasia/Hypoplasia affecting the anterior segment of the eye
HP:0011893	0.0167680508692	0.571428571429	FANCB IL6R FANCC FANCL	Abnormal leukocyte count
HP:0000324	0.0168345656332	0.428571428571	FANCB FANCC FANCL	Facial asymmetry
HP:0010301	0.0172483920487	0.428571428571	FANCB FANCC FANCL	Spinal dysraphism
HP:0003221	0.0174461853129	0.285714285714	FANCL FANCC	Chromosomal breakage induced by crosslinking agents
HP:0009601	0.0176688864012	0.428571428571	FANCB FANCC FANCL	Aplasia/Hypoplasia of the thumb
HP:0002023	0.0180961000944	0.428571428571	FANCB FANCC FANCL	Anal atresia
HP:0008517	0.0199339480346	0.285714285714	FANCB FANCL	Aplasia/Hypoplasia of the sacrum
HP:0000010	0.0208033613994	0.428571428571	FANCB FANCC FANCL	Recurrent urinary tract infections
HP:0004362	0.0212790460403	0.428571428571	FANCB FANCC FANCL	Abnormal enteric ganglion morphology
HP:0002251	0.0212790460403	0.428571428571	FANCB FANCC FANCL	Aganglionic megacolon
HP:0031105	0.0212790460403	0.428571428571	FANCB FANCC FANCL	Abnormal uterus morphology
HP:0025028	0.0217618596498	0.428571428571	FANCB FANCC FANCL	Abnormal enteric nervous system morphology
HP:0025633	0.0217618596498	0.428571428571	FANCB FANCC FANCL	Abnormal ureter morphology
HP:0012331	0.0217618596498	0.428571428571	FANCB FANCC FANCL	Abnormal autonomic nervous system morphology
HP:0040071	0.0222518532316	0.428571428571	FANCB FANCC FANCL	Abnormal morphology of ulna
HP:0001882	0.0227490777452	0.428571428571	FANCB FANCC FANCL	Leukopenia
HP:0012041	0.0232535841056	0.428571428571	FANCB FANCC FANCL	Decreased fertility in males
HP:0002778	0.030497900705	0.428571428571	FANCB FANCC FANCL	Abnormal tracheal morphology
HP:0001646	0.0317294880439	0.428571428571	FANCB FANCC FANCL	Abnormal aortic valve morphology
HP:0012145	0.0323573923258	0.428571428571	FANCB FANCC FANCL	Abnormality of multiple cell lineages in the bone marrow
HP:0010468	0.0349509168675	0.428571428571	FANCB FANCC FANCL	Aplasia/Hypoplasia of the testes
HP:0001562	0.0376778943226	0.428571428571	FANCB FANCC FANCL	Oligohydramnios
HP:0001636	0.0398126266618	0.428571428571	FANCB FANCC FANCL	Tetralogy of Fallot
HP:0010972	0.0420255647459	0.428571428571	FANCB FANCC FANCL	Anemia of inadequate production
HP:0000340	0.0420255647459	0.428571428571	FANCB FANCC FANCL	Sloping forehead
HP:0000172	0.0427808213716	0.428571428571	FANCB FANCC FANCL	Abnormal uvula morphology
HP:0010987	0.0437930719501	0.571428571429	FANCB IL6R FANCC FANCL	Abnormal cellular immune system morphology
HP:0001881	0.0437930719501	0.571428571429	FANCB IL6R FANCC FANCL	Abnormal leukocyte morphology
HP:0045058	0.0451001161404	0.428571428571	FANCB FANCC FANCL	Abnormality of the testis size
HP:0001034	0.0466914108174	0.428571428571	FANCB FANCC FANCL	Hypermelanotic macule
HP:0011017	0.0478764522021	0.571428571429	FANCB IL6R FANCC FANCL	Abnormal cellular physiology
HP:0032251	0.048583388567	0.571428571429	FANCB IL6R FANCC FANCL	Abnormal immune system morphology
HP:0000268	0.0491469862916	0.428571428571	FANCB FANCC FANCL	Dolichocephaly
HP:0009602	0.0491469862916	0.428571428571	FANCB FANCC FANCL	Abnormality of thumb phalanx
HP:0005561	0.0499840105553	0.428571428571	FANCB FANCC FANCL	Abnormal bone marrow cell morphology



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
FANCL	FAAP100	0.995	0.175	hein_WMM     bioplex_WMM     bioplex3_WMM     boldt     hein ()     boldt_WMM
FAAP100	FANCB	0.994	0.124	hein_WMM     bioplex_WMM     bioplex3_WMM     boldt     hein ()     boldt_WMM
FANCL	FANCC	0.994		bioplex3_WMM     bioplex3_HCT116     WMM_only
FANCB	FANCC	0.993		bioplex3_WMM     bioplex3_HCT116     WMM_only
FANCL	FANCB	0.991	0.226	hein_WMM     bioplex_WMM     bioplex3_WMM     boldt     hein ()     boldt_WMM
GRK7	FAAP100	0.988		bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only
CDH16	FANCL	0.975		bioplex3_HEK293     bioplex3_WMM     WMM_only
IL6R	FANCL	0.96		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
IL6R	FANCB	0.96		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
IL6R	FAAP100	0.811		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM





Related Complexes

Genename	Complexes
FANCB	huMAP3_05216.1 huMAP3_05580.1 huMAP3_07422.1 huMAP3_09841.1 huMAP3_10668.1 huMAP3_11458.1 huMAP3_13616.1 huMAP3_13765.1 huMAP3_15070.1 huMAP3_15301.1
FANCL	huMAP3_00342.1 huMAP3_05216.1 huMAP3_05580.1 huMAP3_07422.1 huMAP3_07690.1 huMAP3_09841.1 huMAP3_10668.1 huMAP3_11458.1 huMAP3_13616.1 huMAP3_13765.1 huMAP3_14301.1 huMAP3_15070.1 huMAP3_15301.1
CDH16	huMAP3_00342.1 huMAP3_05216.1 huMAP3_05580.1 huMAP3_07690.1 huMAP3_09841.1 huMAP3_10668.1 huMAP3_11458.1 huMAP3_11598.1 huMAP3_13616.1 huMAP3_13765.1 huMAP3_14301.1
FANCC	huMAP3_07422.1 huMAP3_09841.1 huMAP3_10668.1 huMAP3_11139.1 huMAP3_11458.1 huMAP3_13616.1 huMAP3_13765.1 huMAP3_15070.1 huMAP3_15301.1
GRK7	huMAP3_00382.1 huMAP3_05331.1 huMAP3_10668.1 huMAP3_11458.1 huMAP3_12312.1 huMAP3_13616.1
IL6R	huMAP3_00342.1 huMAP3_00805.1 huMAP3_05216.1 huMAP3_07422.1 huMAP3_09841.1 huMAP3_10668.1 huMAP3_12852.1 huMAP3_12865.1 huMAP3_13096.1 huMAP3_13616.1 huMAP3_15070.1 huMAP3_15315.1
FAAP100	huMAP3_00382.1 huMAP3_05331.1 huMAP3_10668.1 huMAP3_11458.1 huMAP3_12312.1 huMAP3_13616.1 huMAP3_15070.1