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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_10674.1
Complex Portal:
CPX-19639
Confidence:
Medium High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
CCN2
CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8)
5
UniProt
NCBI
CCNA1
Cyclin-A1
5
UniProt
NCBI
CCNA2
Cyclin-A2 (Cyclin-A) (Cyclin A)
5
UniProt
NCBI
CREBBP
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
5
UniProt
NCBI
EP300
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
5
UniProt
NCBI
HELB
DNA helicase B (hDHB) (EC 3.6.4.12)
5
UniProt
NCBI
RBL1
Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1)
5
UniProt
NCBI
RBL2
Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)
5
UniProt
NCBI
SCAPER
S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291)
5
UniProt
NCBI
TICRR
Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)
5
UniProt
NCBI
Showing 1 to 10 of 10 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
KEGG:04110
1.95496433217e-11
0.777777777778
EP300 RBL2 CCNA1 TICRR CCNA2 RBL1 CREBBP
Cell cycle
REAC:R-HSA-6791312
6.50968603152e-09
0.555555555556
EP300 CCNA2 CCNA1 RBL1 RBL2
TP53 Regulates Transcription of Cell Cycle Genes
KEGG:05203
1.61279345025e-08
0.666666666667
EP300 RBL2 CCNA1 CCNA2 RBL1 CREBBP
Viral carcinogenesis
REAC:R-HSA-1538133
2.33494282896e-07
0.444444444444
RBL2 CCNA2 CCNA1 RBL1
G0 and Early G1
KEGG:05165
2.54270193537e-07
0.666666666667
EP300 RBL2 CCNA1 CCNA2 RBL1 CREBBP
Human papillomavirus infection
WP:WP179
3.23734328883e-07
0.555555555556
EP300 CCNA2 CCNA1 RBL1 RBL2
Cell cycle
REAC:R-HSA-3700989
2.74865812668e-06
0.666666666667
EP300 RBL2 CCNA1 CCNA2 RBL1 CREBBP
Transcriptional Regulation by TP53
REAC:R-HSA-1362300
1.73466913202e-05
0.333333333333
RBL2 CCNA2 RBL1
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
REAC:R-HSA-6804114
2.59087532521e-05
0.333333333333
EP300 RBL1 RBL2
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
WP:WP366
4.6548465939e-05
0.444444444444
EP300 CREBBP RBL1 RBL2
TGF beta signaling pathway
Showing 1 to 10 of 134 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
RBL2
CCNA2
1.0
0.118
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM
RBL1
CCNA2
1.0
0.296
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
SCAPER
CCNA2
0.999
0.176
structurally_consistent (dimer)
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116
EP300
CREBBP
0.999
0.476
bioplex_WMM bioplex3_WMM boldt youn_WMM fraction boldt_WMM
RBL2
RBL1
0.996
0.118
bioplex_WMM bioplex3_WMM WMM_only boldt_WMM
CREBBP
CCNA2
0.996
0.236473684211
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM
EP300
CCNA2
0.995
0.266809384164
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM
CCNA2
CCNA1
0.993
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
CCN2
EP300
0.979
0.072
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
TICRR
CCNA2
0.955
0.152
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
Showing 1 to 10 of 38 entries
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Related Complexes
Genename
Complexes
EP300
huMAP3_00314.1
huMAP3_01026.1
huMAP3_04432.1
huMAP3_06547.1
huMAP3_06587.1
huMAP3_08026.1
huMAP3_09145.1
huMAP3_10449.1
huMAP3_10674.1
huMAP3_10958.1
huMAP3_12894.1
huMAP3_12923.1
huMAP3_14722.1
RBL2
huMAP3_00487.1
huMAP3_03477.1
huMAP3_05947.1
huMAP3_06587.1
huMAP3_08026.1
huMAP3_09145.1
huMAP3_10449.1
huMAP3_10674.1
huMAP3_10910.1
huMAP3_11168.1
huMAP3_12923.1
huMAP3_14722.1
CCN2
huMAP3_00314.1
huMAP3_01600.1
huMAP3_04432.1
huMAP3_05377.1
huMAP3_08477.1
huMAP3_10674.1
huMAP3_10958.1
huMAP3_14435.1
TICRR
huMAP3_00407.1
huMAP3_05269.1
huMAP3_07430.1
huMAP3_10674.1
huMAP3_11496.1
HELB
huMAP3_01029.1
huMAP3_05269.1
huMAP3_07430.1
huMAP3_10674.1
huMAP3_13731.1
huMAP3_14318.1
RBL1
huMAP3_00487.1
huMAP3_03164.1
huMAP3_03477.1
huMAP3_05269.1
huMAP3_05947.1
huMAP3_06587.1
huMAP3_08026.1
huMAP3_09145.1
huMAP3_10449.1
huMAP3_10674.1
huMAP3_10910.1
huMAP3_11168.1
huMAP3_12894.1
huMAP3_12923.1
huMAP3_14722.1
SCAPER
huMAP3_01026.1
huMAP3_05269.1
huMAP3_07430.1
huMAP3_08026.1
huMAP3_09145.1
huMAP3_10449.1
huMAP3_10674.1
huMAP3_14365.1
huMAP3_14722.1
CREBBP
huMAP3_01026.1
huMAP3_02340.1
huMAP3_04432.1
huMAP3_06547.1
huMAP3_06587.1
huMAP3_08026.1
huMAP3_09145.1
huMAP3_10449.1
huMAP3_10674.1
huMAP3_10958.1
huMAP3_12894.1
huMAP3_12923.1
huMAP3_14722.1
CCNA2
huMAP3_01026.1
huMAP3_05269.1
huMAP3_06587.1
huMAP3_07430.1
huMAP3_08026.1
huMAP3_09145.1
huMAP3_10449.1
huMAP3_10674.1
huMAP3_14722.1
CCNA1
huMAP3_01026.1
huMAP3_05269.1
huMAP3_07430.1
huMAP3_08026.1
huMAP3_09145.1
huMAP3_10449.1
huMAP3_10674.1
huMAP3_14722.1