hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10676.1
Complex Portal: CPX-12825
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RAB4B | Ras-related protein Rab-4B (EC 3.6.5.2) | 5 | UniProt NCBI |
| ACY1 | Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) | 5 | UniProt NCBI |
| RAB4A | Ras-related protein Rab-4A (EC 3.6.5.2) | 5 | UniProt NCBI |
| NUDT1 | Oxidized purine nucleoside triphosphate hydrolase (EC 3.6.1.56) (2-hydroxy-dATP diphosphatase) (7,8-dihydro-8-oxoguanine triphosphatase) (8-oxo-dGTPase) (Methylated purine nucleoside triphosphate hydrolase) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5579007 | 0.0498224659464 | 0.333333333333 | ACY1 | Defective ACY1 causes encephalopathy |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RAB4B | RAB4A | 0.998 | 0.162 |
mutually_exclusive (P31150)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| RAB4A | ACY1 | 0.981 | 0.05 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NUDT1 | ACY1 | 0.967 | 0.032 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction | |
| RAB4B | ACY1 | 0.306 | 0.034 | bioplex3_WMM WMM_only | |
| RAB4A | NUDT1 | 0.002 | 0.076 | bioplex3_HEK293 bioplex3_HCT116 WMM_only |
Related Complexes