hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10684.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INTS6 | Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1) | 5 | UniProt NCBI |
| INTS3 | Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) | 5 | UniProt NCBI |
| DIAPH3 | Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (MDia2) | 5 | UniProt NCBI |
| INIP | SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1) (hSSBIP1) | 5 | UniProt NCBI |
| NABP2 | SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1) | 5 | UniProt NCBI |
| MIGA1 | Mitoguardin 1 (Protein FAM73A) | 5 | UniProt NCBI |
| INTS6L | Integrator complex subunit 6-like (Protein DDX26B) | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070876 | 1.34540429244e-05 | 0.428571428571 | NABP2 INTS3 INIP | SOSS complex |
| REAC:R-HSA-6807505 | 0.000766722633593 | 0.428571428571 | NABP2 INTS6 INTS3 | RNA polymerase II transcribes snRNA genes |
| CORUM:1153 | 0.00135166454364 | 0.285714285714 | INTS6 INTS3 | Integrator complex |
| CORUM:1155 | 0.00159705726664 | 0.285714285714 | INTS6 INTS3 | Integrator-RNAPII complex |
| GO:0032039 | 0.0032492156641 | 0.428571428571 | INTS6 INTS6L INTS3 | integrator complex |
| GO:0016180 | 0.00870569405676 | 0.428571428571 | INTS6 INTS6L INTS3 | snRNA processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NABP2 | INTS3 | 1.0 | 0.33 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () Malo bioplex3_HCT116 fraction |
| INIP | NABP2 | 1.0 | 0.282 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () Malo bioplex3_HCT116 fraction |
| INIP | INTS3 | 0.999 | 0.396 | hein_WMM bioplex_WMM bioplex3_WMM Malo fraction |
| NABP2 | INTS6 | 0.985 | 0.198 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MIGA1 | INTS3 | 0.982 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only |
| NABP2 | INTS6L | 0.978 | 0.056 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| INIP | MIGA1 | 0.974 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| INTS6 | INTS3 | 0.971 | 0.308 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| MIGA1 | DIAPH3 | 0.964 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only |
| INIP | DIAPH3 | 0.959 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only |
| MIGA1 | NABP2 | 0.895 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only |
| INTS3 | DIAPH3 | 0.892 | 0.098 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| NABP2 | DIAPH3 | 0.891 | 0.118 | bioplex_WMM bioplex3_WMM WMM_only |
| INTS6L | INTS6 | 0.84 | 0.06 | bioplex3_WMM WMM_only |
| INIP | INTS6 | 0.802 | 0.158 | hein_WMM bioplex3_WMM WMM_only |
| INTS6L | INTS3 | 0.761 | 0.092 | bioplex3_WMM WMM_only |
| INIP | INTS6L | 0.72 | 0.108 | bioplex3_WMM WMM_only |
| MIGA1 | INTS6L | 0.026 | 0.08 | bioplex3_WMM WMM_only |
Related Complexes