hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10690.1
Complex Portal: CPX-20651
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NPNT | Nephronectin (Preosteoblast EGF-like repeat protein with MAM domain) (Protein EGFL6-like) | 5 | UniProt NCBI |
| BCHE | Cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase) (Butyrylcholine esterase) (Choline esterase II) (Pseudocholinesterase) | 5 | UniProt NCBI |
| ADAM17 | Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b) | 5 | UniProt NCBI |
| PRIMA1 | Proline-rich membrane anchor 1 (PRiMA) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2645 | 0.0373138951921 | 0.25 | BCHE | Heroin metabolism |
| WP:WP2826 | 0.049746753544 | 0.25 | BCHE | Cocaine metabolism |
| WP:WP5076 | 0.049746753544 | 0.25 | ADAM17 | Soluble ACE2 mediated cell entry of SARS CoV 2 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BCHE | NPNT | 0.981 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ADAM17 | BCHE | 0.979 | 0.132 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| PRIMA1 | BCHE | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PRIMA1 | NPNT | 0.487 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes