hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10698.1
Complex Portal: CPX-13666
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF136 | Zinc finger protein 136 | 4 | UniProt NCBI |
| ZNF358 | Zinc finger protein 358 | 3 | UniProt NCBI |
| LTBP1 | Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) | 5 | UniProt NCBI |
| EFEMP1 | EGF-containing fibulin-like extracellular matrix protein 1 (Extracellular protein S1-5) (Fibrillin-like protein) (Fibulin-3) (FIBL-3) | 5 | UniProt NCBI |
| ZNF628 | Zinc finger protein 628 | 4 | UniProt NCBI |
| LOXL1 | Lysyl oxidase homolog 1 (EC 1.4.3.13) (Lysyl oxidase-like protein 1) (LOL) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1566948 | 5.02070457715e-05 | 0.5 | LTBP1 LOXL1 EFEMP1 | Elastic fibre formation |
| HP:0012636 | 0.000648041335154 | 0.333333333333 | EFEMP1 LOXL1 | Retinal vein occlusion |
| REAC:R-HSA-2129379 | 0.0104313293282 | 0.333333333333 | LTBP1 EFEMP1 | Molecules associated with elastic fibres |
| REAC:R-HSA-1474244 | 0.0133066815994 | 0.5 | LTBP1 LOXL1 EFEMP1 | Extracellular matrix organization |
| HP:0012633 | 0.0349615340576 | 0.333333333333 | EFEMP1 LOXL1 | Asymmetry of intraocular pressure |
| HP:0012632 | 0.037751561683 | 0.333333333333 | EFEMP1 LOXL1 | Abnormal intraocular pressure |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF358 | EFEMP1 | 0.993 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| EFEMP1 | LTBP1 | 0.98 | 0.156 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ZNF628 | EFEMP1 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| EFEMP1 | LOXL1 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF136 | EFEMP1 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF136 | ZNF628 | 0.612 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF358 | ZNF136 | 0.428 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF358 | ZNF628 | 0.304 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF628 | LTBP1 | 0.218 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF136 | LTBP1 | 0.211 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF358 | LTBP1 | 0.194 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF358 | LOXL1 | 0.187 | bioplex_WMM bioplex3_WMM WMM_only | ||
| LOXL1 | LTBP1 | 0.18 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF136 | LOXL1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF628 | LOXL1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes