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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_10702.1
Complex Portal:
CPX-20960
Confidence:
Medium High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
DBT
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (BCKDH-E2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)
5
UniProt
NCBI
DLD
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)
5
UniProt
NCBI
DLST
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K)
5
UniProt
NCBI
KGD4
Alpha-ketoglutarate dehydrogenase component 4 (Alpha-ketoglutarate dehydrogenase subunit 4)
3
UniProt
NCBI
OGDH
2-oxoglutarate dehydrogenase complex component E1 (E1o) (OGDC-E1) (OGDH-E1) (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Alpha-KGDH-E1) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase)
5
UniProt
NCBI
OGDHL
2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like)
5
UniProt
NCBI
PAGE2B
Putative G antigen family E member 3 (Prostate-associated gene 2B protein) (PAGE-2B)
2
UniProt
NCBI
TCAIM
T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1)
3
UniProt
NCBI
Showing 1 to 8 of 8 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
GO:0045252
3.97003041564e-12
0.714285714286
DLST OGDH DLD OGDHL KGD4
oxoglutarate dehydrogenase complex
GO:0045240
8.73008139488e-11
0.714285714286
DLST OGDH DLD OGDHL KGD4
dihydrolipoyl dehydrogenase complex
GO:0045239
1.16850131892e-09
0.714285714286
DLST OGDH DLD OGDHL KGD4
tricarboxylic acid cycle enzyme complex
KEGG:00785
2.93487162541e-09
0.571428571429
DLST OGDH OGDHL DLD
Lipoic acid metabolism
KEGG:01210
2.62325515445e-08
0.571428571429
DLST OGDH OGDHL DLD
2-Oxocarboxylic acid metabolism
KEGG:00020
2.62325515445e-08
0.571428571429
DLST OGDH OGDHL DLD
Citrate cycle (TCA cycle)
CORUM:7267
2.80877722849e-08
0.428571428571
DLST DLD OGDH
KAT2A-Oxoglutarate dehydrogenase complex
GO:0006103
6.57500588447e-07
0.571428571429
DLST OGDH OGDHL KGD4
2-oxoglutarate metabolic process
REAC:R-HSA-71064
2.1479923589e-06
0.428571428571
DLST DLD OGDH
Lysine catabolism
GO:0004591
3.36420143768e-06
0.428571428571
OGDH OGDHL KGD4
oxoglutarate dehydrogenase (succinyl-transferring) activity
Showing 1 to 10 of 38 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
OGDH
DLST
1.0
0.658
mutually_exclusive (Q9ULD0)
hein_WMM bioplex_WMM Guru bioplex3_WMM boldt youn_WMM Malo fraction boldt_WMM
OGDHL
DLD
1.0
0.332
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
OGDH
KGD4
0.999
0.512
hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only
KGD4
DLST
0.999
0.336
hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only
OGDHL
DLST
0.999
0.74
structurally_consistent (dimer)
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
DLD
DLST
0.998
0.736
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM Malo fraction boldt_WMM treiber_WMM
DLD
KGD4
0.998
0.346
structurally_consistent (dimer)
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction
OGDHL
OGDH
0.998
0.966
structurally_consistent (dimer)
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
OGDHL
KGD4
0.997
0.53
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
DLD
OGDH
0.995
0.478
mutually_exclusive (Q9ULD0)
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM
Showing 1 to 10 of 27 entries
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Related Complexes
Genename
Complexes
TCAIM
huMAP3_04997.1
huMAP3_07213.1
huMAP3_10702.1
huMAP3_11548.1
huMAP3_11871.1
huMAP3_12906.1
huMAP3_13605.1
huMAP3_14640.1
OGDHL
huMAP3_03032.1
huMAP3_10702.1
huMAP3_11548.1
huMAP3_11871.1
huMAP3_12906.1
huMAP3_13605.1
KGD4
huMAP3_07213.1
huMAP3_10702.1
huMAP3_11548.1
huMAP3_11871.1
huMAP3_12248.1
huMAP3_13605.1
DBT
huMAP3_03551.1
huMAP3_07213.1
huMAP3_10244.1
huMAP3_10702.1
huMAP3_12248.1
huMAP3_12775.1
PAGE2B
huMAP3_03032.1
huMAP3_10702.1
huMAP3_11548.1
huMAP3_11871.1
huMAP3_12085.1
huMAP3_12906.1
huMAP3_13358.1
huMAP3_13605.1
DLD
huMAP3_04997.1
huMAP3_07213.1
huMAP3_10702.1
huMAP3_11548.1
huMAP3_11871.1
huMAP3_12248.1
huMAP3_14864.1
DLST
huMAP3_07213.1
huMAP3_10702.1
huMAP3_11548.1
huMAP3_11871.1
huMAP3_12906.1
huMAP3_13605.1
OGDH
huMAP3_04997.1
huMAP3_07213.1
huMAP3_10702.1
huMAP3_11548.1
huMAP3_11871.1
huMAP3_12906.1
huMAP3_13605.1