hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10724.1
Complex Portal: CPX-25472
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HSPA12B | Heat shock 70 kDa protein 12B | 4 | UniProt NCBI |
| PODXL | Podocalyxin (GCTM-2 antigen) (Gp200) (Podocalyxin-like protein 1) (PC) (PCLP-1) | 5 | UniProt NCBI |
| NATD1 | Protein NATD1 (N-acetyltransferase domain-containing protein 1) | 3 | UniProt NCBI |
| HSPA12A | Heat shock 70 kDa protein 12A | 4 | UniProt NCBI |
| AKAP12 | A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen) | 5 | UniProt NCBI |
| PTPRG | Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3371453 | 0.0313469851718 | 0.4 | HSPA12B HSPA12A | Regulation of HSF1-mediated heat shock response |
| HPA:0271113 | 0.0488881871595 | 0.4 | AKAP12 PODXL | kidney; bowman's capsule[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HSPA12B | HSPA12A | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AKAP12 | HSPA12A | 0.998 | 0.168 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| HSPA12B | PODXL | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PODXL | NATD1 | 0.981 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PTPRG | PODXL | 0.966 | 0.106 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| PODXL | HSPA12A | 0.956 | 0.04 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| HSPA12B | AKAP12 | 0.916 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| PTPRG | AKAP12 | 0.079 | 0.148 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| NATD1 | HSPA12A | 0.03 | bioplex3_WMM WMM_only | ||
| HSPA12B | NATD1 | 0.013 | bioplex3_WMM WMM_only | ||
| PODXL | AKAP12 | 0.008 | 0.306 |
mutually_exclusive (O43301)
|
bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| PTPRG | HSPA12A | 0.007 | 0.04 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
Related Complexes