hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10740.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HLA-DRB5 | HLA class II histocompatibility antigen, DR beta 5 chain (DR beta-5) (DR2-beta-2) (Dw2) (MHC class II antigen DRB5) | 5 | UniProt NCBI |
| UGGT1 | UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1) | 5 | UniProt NCBI |
| MOGS | Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-532668 | 0.00381957013228 | 0.666666666667 | MOGS UGGT1 | N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| KEGG:04141 | 0.00916431091176 | 0.666666666667 | MOGS UGGT1 | Protein processing in endoplasmic reticulum |
| REAC:R-HSA-4793954 | 0.0498224659464 | 0.333333333333 | MOGS | Defective MOGS causes CDG-2b |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MOGS | UGGT1 | 0.965 | 0.412 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM treiber_WMM WMM_only |
| HLA-DRB5 | MOGS | 0.963 | 0.176425806452 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| HLA-DRB5 | UGGT1 | 0.521 | 0.18 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| HLA-DRB5 | huMAP3_03618.1 huMAP3_05213.1 huMAP3_06470.1 huMAP3_09938.1 huMAP3_10740.1 |
| UGGT1 | huMAP3_08545.1 huMAP3_10740.1 huMAP3_12557.1 huMAP3_14946.1 |
| MOGS | huMAP3_03618.1 huMAP3_10740.1 |